What is Embark?

Addy

Tap to enlarge

See what’s hidden in the pages of Addy’s DNA story. You can learn about the breeds that make Addy who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

Genetic Stats

Wolfiness: 2.5 % HIGH Help
Predicted Adult Weight: 74 lbs Help
Genetic Age: 23 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Addy

Breed Mix By Chromosome

Our advanced test identifies from where Addy inherited every part of the chromosome pairs in her genome. Each chromosome section is colored to represent the breed that it comes from.

Family tree

>
Explore an interactive family tree and get a picture of Addy’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Addy.

Maternal Line

>
Through the DNA inherited from Addy’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Addy’s family has traveled.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
Explore by tapping your dog’s parents and grand parents.

Our algorithms predict this is the most likely family tree to explain Addy’s breed mix, but this family tree may not be the only possible one.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Addy.

Maternal Line

>
Through the DNA inherited from Addy’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Addy’s family has traveled.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Doberman Pinscher
3 related breeds
Doberman Pinscher
Doberman Pinscher’s are a strong and athletic breed that are built to guard and protect.
Related Breeds
Standard Schnauzer
Sibling breed
Giant Schnauzer
Sibling breed
Miniature Schnauzer
Sibling breed
Great Pyrenees
3 related breeds
Great Pyrenees
The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, and any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.
Related Breeds
Pyrenean Mastiff
Sibling breed
Pyrenean Shepherd
Cousin breed
Anatolian Shepherd Dog
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Addy’s family.

Maternal Line

>
Through the DNA inherited from Addy’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Addy’s family has traveled.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Addy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A25

A1e

Addy’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A25

Addy’s Haplotype

Part of the large A1e haplogroup, we have detected this haplotype in village dogs in Mexico. We also see it in Irish Wolfhounds, Great Pyrenees, Brittanys, and Labrador Retrievers.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

Family tree

>
Explore an interactive family tree and get a picture of Addy’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Addy.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aya or ayat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GT
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CT
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of Addy’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Addy.

Maternal Line

>
Through the DNA inherited from Addy’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Addy’s family has traveled.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
158
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Addy has two normal alleles at ALT.

Not At Risk

Good news! Addy did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Addy does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Addy’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Addy is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Addy tested clear for 5 genetic conditions that are common in her breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Great Pyreneess, but not Addy.

Glanzmann's Thrombasthenia Type I
(ITGA2B Exon 13)
Blood

A disease of defective platelet aggregation, this causes affected dogs to bleed excessively in response to mild tissue trauma. Platelets are the first responders to tissu…

Seen in Great Pyreneess, but not Addy.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a nonprogressive retinal disease that, in rare cases, can lead to vision loss. All known mutations lie in the BEST1 gene and are inherited in an autosomal recessi…

Seen in Great Pyreneess, but not Addy.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Doberman Pinschers, Great Pyreneess, but not Addy.

Dilated Cardiomyopathy
(PDK4)
Heart

The most common acquired heart disease of dogs, this is a progressive disease of the heart ventricles: early diagnosis and treatment is key. The ventricles are the heavil…

Seen in Doberman Pinschers, but not Addy.

Other Conditions: Clear of 153

Addy is clear of 153 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Addy’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Addy.

Maternal Line

>
Through the DNA inherited from Addy’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Addy’s family has traveled.

Let us know and we will contact Addy’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Addy find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit