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Akira

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See what’s hidden in the pages of Akira’s DNA story. You can learn about the breeds that make Akira who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

“Akira is a foster failure. She is an excellent companion for bikejoring. Exceptionally intelligent and fast.”

Genetic Stats

Wolfiness: 2.5 % HIGH Help
Predicted Adult Weight: 59 lbs Help
Genetic Age: 44 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Akira

Breed Mix By Chromosome

Our advanced test identifies from where Akira inherited every part of the chromosome pairs in her genome.

Family tree

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Explore an interactive family tree and get a picture of Akira’s family.

Breed Families

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Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Akira.

Maternal Line

>
Through the DNA inherited from Akira’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Akira’s family has traveled.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Akira.

Maternal Line

>
Through the DNA inherited from Akira’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Akira’s family has traveled.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Siberian Husky
3 related breeds
Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
Related Breeds
Alaskan Malamute
Sibling breed
Greenland Sledge Dog
Sibling breed
Samoyed
Cousin breed
Samoyed
3 related breeds
Samoyed
A working breed, the Samoyed can be strong-willed at times, but above all they remain friendly, gentle, and devoted family dogs. The Samoyed was originally bred to hunt, haul sledges, and herd reindeer. Among the breed’s duties: pack hiking, tracking, and warming their owners by sleeping on top of them at night.
Related Breeds
Eurasier
Sibling breed
American Eskimo Dog
Sibling breed
Icelandic Sheepdog
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Akira’s family.

Maternal Line

>
Through the DNA inherited from Akira’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Akira’s family has traveled.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Akira’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A266

A1a

Akira’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A266

Akira’s Haplotype

Part of the large A1a haplogroup, this uncommon haplotype occurs in dogs with European ancestry.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Family tree

>
Explore an interactive family tree and get a picture of Akira’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Akira.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e).

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aa or ata or atat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GT
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CC
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Genetic Diversity

Inbreeding is a meaure of how closely related your dog’s parents were. The higher the inbreeding coefficient, the more closely related the parents. In general, higher inbreeding coefficients are associated with increased incidence of genetically inherited conditions.

Diversity of the maternal and paternal haplotypes in the Major Histocompatibility Complex (MHC) region of the genome has been found in some studies to be associated with the incidence of certain autoimmune diseases. Dogs that have less diversity in the MHC region haplotypes—i.e. the Dog Leukocyte Antigen (DLA) inherited from the mother is similar to the DLA inherited from the father—are considered less immunologically diverse. A High Diversity result means the dog has two highly dissimilar haplotypes. A Low Diversity result means the dog has two similar but not identical haplotypes. A No Diversity result means the dog has inherited identical haplotypes from both parents.

Inbreeding Coefficient
7%

Measures the proportion of the genome where the genes on the mother’s side are identical by descent to those on the father’s side.

This chart shows how common various inbreeding levels are in different groups of dogs. At the left are dogs with 0% inbreeding, i.e. completely outbred. As you look right, the amount of inbreeding increases. The height of the line shows how many dogs have that amount of inbreeding. The arrow shows where Akira fits into this picture.
MHC Class II - DLA DRB1
High Diversity
Chromosome 12

A Dog Leukocyte Antigen (DLA) gene, DRB1 encodes a major histocompatibility complex (MHC) protein involved in the immune response. Some studies have shown associations between certain DRB1 haplotypes and autoimmune diseases such as Cushing's disease, but these findings have yet to be scientifically validated.

How common is this amount of diversity in mixed breed dogs?

Citations: Angles et al 2005

MHC Class II - DLA DQA1 and DQB1
High Diversity
Chromosome 12

DQA1 and DQB1 are two tightly linked DLA genes that code for MHC proteins involved in the immune response. A number of studies have shown correlations of DQA-DQB1 haplotypes and certain autoimmune diseases; however, these have not yet been scientifically validated.

How common is this amount of diversity in mixed breed dogs?

Citations: Angles et al 2005

Family tree

>
Explore an interactive family tree and get a picture of Akira’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Akira.

Maternal Line

>
Through the DNA inherited from Akira’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Akira’s family has traveled.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
160
CLEAR
Tap above or scroll down to see more
Go to VET REPORT to easily share this information with your veterinarian.

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Akira has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Akira has thi…

Not At Risk

Good news! Akira did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Akira does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Akira’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Akira is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Akira tested clear for 3 other genetic conditions that are common in her breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Siberian Huskys, Samoyeds, but not Akira.

X-Linked Hereditary Nephropathy
(COL4A5 Exon 35)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in Samoyeds, but not Akira.

Degenerative Myelopathy
(SOD1 Exon 2)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Siberian Huskys, Samoyeds, but not Akira.

Other Conditions: Clear of 157

Akira is clear of 157 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Akira’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Akira.

Maternal Line

>
Through the DNA inherited from Akira’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Akira’s family has traveled.

Let us know and we will contact Akira’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Akira find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit