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“Dash”
FC Skalkaho’s Fiery Brown

English Cocker Spaniel (Working Type)

No bio has been provided yet

Place of Birth

Hamilton, Montana, USA

Current Location

Hamilton, Montana, USA

From

Hamilton, Montana, USA

This dog has been viewed and been given 3 wags

Registration

American Kennel Club (AKC): SR67900102

Genetic Breed Result

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English Cocker Spaniel (Working Type)

English Cockers are a medium-size dog with long ears and a happy disposition. The name Cocker comes from their use to hunt woodcock in England, although English Cockers have been used to hunt many other types of birds as well. They make great companion dogs for people who can give them the exercise they need. A field-bred cocker spaniel is first and foremost an upland flushing dog, bred for skills like hup, retrieve to hand, quarter, follow hand signals, and steady.

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Changes to this dog’s profile
  • On 12/1/2018 changed name from "Dash" to "Skalkaho’s Fiery Brown"
Here’s what Dash’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Dash’s breed mix.
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Health Summary

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Dash is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Dash inherited both copies of the variant we tested

How to interpret this result

Dash has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Dash inherited both copies of the variant we tested

Why is this important to your vet?

Dash has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Dash's ALT activity above their current, healthy, ALT activity. As an increase above Dash’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Working-type English Cocker Spaniels

Familial Nephropathy (COL4A4 Exon 3, Cocker Spaniel Variant)

Identified in Working-type English Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in Working-type English Cocker Spaniels

Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant)

Identified in Working-type English Cocker Spaniels

Exercise-Induced Collapse, EIC (DNM1)

Identified in Working-type English Cocker Spaniels

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Dash’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B6/8/67

Map

B1

Skalkaho’s Fiery Brown’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B6/8/67

Skalkaho’s Fiery Brown’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in village dogs from South America to the Middle East, all the way down to the French Polynesian Islands. Among the 12 breed dogs we have seen it in, it occurs most frequently among German Shepherd Dogs, English Springer Spaniels, and Havanese.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Dash inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Dash is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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