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Delilah

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See what’s hidden in the pages of Delilah’s DNA story. You can learn about the breeds that make Delilah who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

“Delilah is a rescue from Tennessee- she was found as a stray and then a rescue saved her from being euthanized at the pound. I've had Delilah for over a year now. Super high prey drive, very smart but not a great understanding of the physical world. She has been diagnosed with luxating patellas in both legs as well as Canine Compulsive Disorder. She is very nervous around people but loves dogs. She loves hiking, playing, snuggling, hunting small animals, and training.”

Genetic Stats

Wolfiness: 0.8 % MEDIUM Help
Predicted Adult Weight: 18 lbs Help
Genetic Age: 25 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Delilah

Breed Mix By Chromosome

Our advanced test identifies from where Delilah inherited every part of the chromosome pairs in her genome.

Family tree

>
Explore an interactive family tree and get a picture of Delilah’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Delilah.

Maternal Line

>
Through the DNA inherited from Delilah’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Delilah’s family has traveled.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Delilah.

Maternal Line

>
Through the DNA inherited from Delilah’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Delilah’s family has traveled.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Russell-type Terrier
2 related breeds
Russell-type Terrier
These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.
Related Breeds
Wire Fox Terrier
Sibling breed
Rat Terrier
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Delilah’s family.

Maternal Line

>
Through the DNA inherited from Delilah’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Delilah’s family has traveled.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Delilah’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

A1d

Delilah’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

Delilah’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

Family tree

>
Explore an interactive family tree and get a picture of Delilah’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Delilah.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EmEm
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e).

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aya or ayat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GG
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
TT
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

IGF1
II
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

STC2
AA
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Genetic Diversity

Inbreeding is a meaure of how closely related your dog’s parents were. The higher the inbreeding coefficient, the more closely related the parents. In general, higher inbreeding coefficients are associated with increased incidence of genetically inherited conditions.

Diversity of the maternal and paternal haplotypes in the Major Histocompatibility Complex (MHC) region of the genome has been found in some studies to be associated with the incidence of certain autoimmune diseases. Dogs that have less diversity in the MHC region haplotypes—i.e. the Dog Leukocyte Antigen (DLA) inherited from the mother is similar to the DLA inherited from the father—are considered less immunologically diverse. A High Diversity result means the dog has two highly dissimilar haplotypes. A Low Diversity result means the dog has two similar but not identical haplotypes. A No Diversity result means the dog has inherited identical haplotypes from both parents.

Inbreeding Coefficient
47%

Measures the proportion of the genome where the genes on the mother’s side are identical by descent to those on the father’s side.

This chart shows how common various inbreeding levels are in different groups of dogs. At the left are dogs with 0% inbreeding, i.e. completely outbred. As you look right, the amount of inbreeding increases. The height of the line shows how many dogs have that amount of inbreeding. The arrow shows where Delilah fits into this picture.
MHC Class II - DLA DRB1
No Diversity
Chromosome 12

A Dog Leukocyte Antigen (DLA) gene, DRB1 encodes a major histocompatibility complex (MHC) protein involved in the immune response. Some studies have shown associations between certain DRB1 haplotypes and autoimmune diseases such as Cushing's disease, but these findings have yet to be scientifically validated.

How common is this amount of diversity in mixed breed dogs?

Citations: Angles et al 2005

MHC Class II - DLA DQA1 and DQB1
No Diversity
Chromosome 12

DQA1 and DQB1 are two tightly linked DLA genes that code for MHC proteins involved in the immune response. A number of studies have shown correlations of DQA-DQB1 haplotypes and certain autoimmune diseases; however, these have not yet been scientifically validated.

How common is this amount of diversity in mixed breed dogs?

Citations: Angles et al 2005

Family tree

>
Explore an interactive family tree and get a picture of Delilah’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Delilah.

Maternal Line

>
Through the DNA inherited from Delilah’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Delilah’s family has traveled.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
160
CLEAR
Tap above or scroll down to see more
Go to VET REPORT to easily share this information with your veterinarian.

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Delilah has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that Delilah has this genotype, as ALT is often used as an indi…

Not At Risk

Good news! Delilah did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Delilah does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Delilah’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Delilah is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Delilah tested clear for 9 other genetic conditions that are common in her breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Russell-type Terriers, Rat Terriers, but not Delilah.

Congenital hypothyroidism
(TPO Variant 1)
Hormones

This a medically manageable condition that arises from an inherent inability to produce the hormone thyroxine. Congenitally hypothyroid pups are usually lethargic and ove…

Seen in Rat Terriers, but not Delilah.

Severe Combined Immunodeficiency
(PRKDC)
Immune

As can be surmised from the name, this is a deficiency of multiple immune components: affected dogs require close monitoring for signs of infection, and should not be adm…

Seen in Russell-type Terriers, but not Delilah.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Russell-type Terriers, Rat Terriers, but not Delilah.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in Russell-type Terriers, but not Delilah.

Spinocerebellar Ataxia, Late-Onset Ataxia
(CAPN1)
Brain and Spinal Cord

Known as the most primordial part of the brain, the cerebellum fine tunes motor signals from the brain to the muscles, allowing for balance and coordination. Symptoms of …

Seen in Russell-type Terriers, but not Delilah.

Spinocerebellar Ataxia with Myokymia and/or Seizures
(KCNJ10)
Brain and Spinal Cord

Known as the most primordial part of the brain, the cerebellum fine tunes motor signals from the brain to the muscles, allowing for balance and coordination. Symptoms of …

Seen in Russell-type Terriers, but not Delilah.

Degenerative Myelopathy
(SOD1 Exon 2)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Russell-type Terriers, Rat Terriers, but not Delilah.

Dilated Cardiomyopathy
(PDK4)
Heart

The most common cardiac disease of dogs, this is a progressive disease of the heart ventricles: early diagnosis and treatment is key. The ventricles are the heavily muscl…

Seen in Russell-type Terriers, but not Delilah.

Other Conditions: Clear of 151

Delilah is clear of 151 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Delilah’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Delilah.

Maternal Line

>
Through the DNA inherited from Delilah’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Delilah’s family has traveled.

Let us know and we will contact Delilah’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

Contact us

What’s your dog’s story?

Now that you have explored what’s behind Delilah find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit