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Shakira inherited one copy of the variant we tested
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Place of Birth
San Antonio, TX, USA
Current Location
St. Louis, Missouri, USA
From
San Antonio, Texas, USA
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Health Summary
Shakira inherited one variant that you should learn more about.
Degenerative Myelopathy, DM
What does this result mean?
This variant should not impact Shakira’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Shakira is unlikely to develop this condition due to this variant because she only has one copy of the variant.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.
What is Degenerative Myelopathy, DM?
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
Breed-Relevant Genetic Conditions
9 variants not detected
Multiple Drug Sensitivity (ABCB1)
Identified in Australian Cattle Dogs
Variant not detected
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Australian Cattle Dogs
Variant not detected
Collie Eye Anomaly (NHEJ1)
Identified in Australian Cattle Dogs
Variant not detected
Primary Lens Luxation (ADAMTS17)
Identified in Australian Cattle Dogs
Variant not detected
Cystinuria Type II-A (SLC3A1, Australian Cattle Dog Variant)
Identified in Australian Cattle Dogs
Variant not detected
Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)
Identified in Australian Cattle Dogs
Variant not detected
Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)
Identified in Australian Cattle Dogs
Variant not detected
GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)
Identified in Siberian Huskies
Variant not detected
Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)
Identified in Australian Cattle Dogs
Variant not detected
Additional Genetic Conditions
155 variants not detected
