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Grace

Mixed Ancestry

“Grace is the sweetest and most graceful lady! Her paws are crossed 99% of the time….unless she needs to paw you gently to ask for more pets! She loves hiking, exploring new places and most of all getting belly rubs!!!”

Instagram tag
@graceful_grace16

Current Location

New Jersey, USA

From

Alabama, USA

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Great Dane

Great Danes are large lovable dogs that need exercise and space. Many Great Danes are "leaners"-- they lean against their people to be closer to them, seemingly oblivious to their size!

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Staffordshire Terrier

Staffordshire Terriers, sometimes referred to as "pit bull" type, are intelligent and trainable dogs. They can have a lot of energy and are often great canine athletes!

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Bloodhound

There’s a reason the saying having a “nose like a Bloodhound” has become so pervasive -- Bloodhounds can track a scent without equal. These substantial hound dogs are easily recognizable due to their long, floppy ears and skin folds, which give them a somewhat comical or soulful expression. This breed is highly social and affectionate, and they will follow their nose wherever it takes them.

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American Bulldog

American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Dogs Like Grace

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Discover dogs who share a similar breed mix to Grace. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Great Dane
Staffordshire Terrier
Bloodhound
American Bulldog
Boxer

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Here’s what Grace’s family tree may have looked like.
Grace
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Great Dane mix Staffordshire Terrier mix Great Dane Great Dane / Bloodhound mix Staffordshire Terrier Bloodhound / American Bulldog mix Great Dane Great Dane Great Dane Bloodhound Staffordshire Terrier Staffordshire Terrier Bloodhound American Bulldog mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Grace’s breed mix.
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Health Summary

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Grace inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Grace inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Grace’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Grace is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Grace inherited one copy of the variant we tested

Why is this important to your vet?

Grace has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Grace has this genotype, as ALT is often used as an indicator of liver health and Grace is likely to have a lower than average resting ALT activity. As such, an increase in Grace’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Hemophilia A

Identified in Boxers

Progressive Retinal Atrophy, crd1

Identified in Staffordshire Terriers

Progressive Retinal Atrophy, crd2

Identified in Staffordshire Terriers

Canine Multifocal Retinopathy, cmr1

Identified in American Bulldogs

Hereditary Cataracts

Identified in Staffordshire Terriers

Urate Kidney & Bladder Stones

Identified in American Bulldogs and Staffordshire Terriers

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in Staffordshire Terriers

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bulldogs

Degenerative Myelopathy, DM

Identified in Bloodhounds and Boxers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in Staffordshire Terriers

Inherited Myopathy of Great Danes

Identified in Great Danes

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Grace’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A234

Map

A1e

Grace’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A234

Grace’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs in village dogs in South America, South Asia, and into the South Pacific. Among breeds, we see it in highest frequency among Vizslas, Boxers, and Yorkshire Terriers.

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Grace inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Grace is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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