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Kefyra

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See what’s hidden in the pages of Kefyra’s DNA story. You can learn about the breeds that make Kefyra who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

Genetic Stats

Wolfiness: 90.6 % HIGH Help
Predicted Adult Weight: 64 lbs Help
Genetic Age: 40 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Kefyra

Breed Mix By Chromosome

Our advanced test identifies from where Kefyra inherited every part of the chromosome pairs in her genome. Each chromosome section is colored to represent the breed that it comes from.

Family tree

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Explore an interactive family tree and get a picture of Kefyra’s family.

Breed Families

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Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Maternal Line

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Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Paternal Line

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The Y-Chromosome is only passed down from father to son. Kefyra’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

At this time, Family Trees are not available for dogs with wild canid heritage.

Most wolfdogs have been deliberately bred and backcrossed for many generations. This is unlike most mixed breed dogs, who are recent crosses from various purebred dogs within 1-3 generations back. Embark strives to provide the most accurate estimate of wild canid heritage possible; because there are several possible ways this wild canid heritage could have been inherited over many generations, we cannot provide estimated 3-generation family trees for wolfdogs.

At this time, Family Trees are not available for dogs with wild canid heritage.

Most wolfdogs have been deliberately bred and backcrossed for many generations. This is unlike most mixed breed dogs, who are recent crosses from various purebred dogs within 1-3 generations back. Embark strives to provide the most accurate estimate of wild canid heritage possible; because there are several possible ways this wild canid heritage could have been inherited over many generations, we cannot provide estimated 3-generation family trees for wolfdogs.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Maternal Line

>
Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Kefyra’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Gray Wolf
4 related breeds
Gray Wolf
They Gray Wolf is the largest of all the wolf species. These are pack animals that are tactical hunters. While they are wild animals, wolves are still able to breed with dogs.
Related Breeds
Central Asian Village Dog
Sibling breed
Red Wolf
Cousin breed
Dire Wolf
Cousin breed
Coyote
Cousin breed
Siberian Husky
3 related breeds
Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
Related Breeds
Alaskan Malamute
Sibling breed
Greenland Sledge Dog
Cousin breed
Samoyed
Cousin breed
Alaskan Malamute
4 related breeds
Alaskan Malamute
The Alaskan Malamute features a powerful, sturdy body built for stamina and strength. It reigns as one of the oldest dog breeds whose original looks have not been significantly altered. This intelligent canine needs a job and consistent leadership to avoid becoming bored or challenging to handle.
Related Breeds
Siberian Husky
Sibling breed
Greenland Sledge Dog
Cousin breed
Chinook
Cousin breed
Carolina Dog
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Kefyra’s family.

Maternal Line

>
Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Kefyra’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Kefyra’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

E

Haplotype

E17

E

Kefyra’s Haplogroup

Haplogroup E is a very rare maternal line, present only in one Akita in our database.

E17

Kefyra’s Haplotype

The E haplogroup in general is not common. It has been found in dogs with East Asian breed ancestry.

Some other Embark dogs with this haplotype:

An example of an Akita.

Family tree

>
Explore an interactive family tree and get a picture of Kefyra’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Kefyra’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

There are no deep ancestral lineage results for Kefyra on her father’s side.

Unlike recent ancestry ("What breeds are in my dog?"), the deep ancestral lineage traces the migration of a dog’s male relatives back in time to the very dawn of dogs.

Male ancestral lineage is passed down father-to-son on the Y sex chromosome. Since female dogs receive two X sex chromosomes and no Y chromosome, their male heritage line is not visible as they have no Y chromosome.

Family tree

>
Explore an interactive family tree and get a picture of Kefyra’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Maternal Line

>
Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aya or ayat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GG
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CC
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of Kefyra’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Maternal Line

>
Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
159
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Kefyra has two normal alleles at ALT.

Not At Risk

Good news! Kefyra did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Kefyra does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Kefyra’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Kefyra is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Kefyra tested clear for 9 genetic conditions that are common in her breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Gray Wolfs, German Shepherd Dogs, Siberian Huskys, Alaskan Malamutes, but not Kefyra.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in German Shepherd Dogs, but not Kefyra.

Canine Leukocyte Adhesion Deficiency Type III
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Kefyra.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in German Shepherd Dogs, but not Kefyra.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia

Seen in German Shepherd Dogs, but not Kefyra.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)

Seen in German Shepherd Dogs, but not Kefyra.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Kefyra.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Gray Wolfs, German Shepherd Dogs, Siberian Huskys, Alaskan Malamutes, but not Kefyra.

Polyneuropathy
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfution. Peripheral nerves relay messages between the brain and spinal cord to the rest …

Seen in Alaskan Malamutes, but not Kefyra.

Other Conditions: Clear of 150

Kefyra is clear of 150 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Kefyra’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Kefyra.

Maternal Line

>
Through the DNA inherited from Kefyra’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Kefyra’s family has traveled.

Let us know and we will contact Kefyra’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Kefyra find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit