What is Embark?

luxx

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See what’s hidden in the pages of luxx’s DNA story. You can learn about the breeds that make luxx who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

“Luxx is part of our JAB Canid Education and Conservation Center. She is a very sweet and loving girl who melts everyone's hearts that meet her. She came to us as a rescue from a zoo and needing a forever home and to be loved. Well, this is a girl you cannot help to fall in love with. To learn more about her and our center, go to www.jabcecc.org”

Genetic Stats

Wolfiness: 3.1 % HIGH Help
Predicted Adult Weight: 46 lbs Help
Genetic Age: 37 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to luxx

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  • Motu
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  • Cameron
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Family tree

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Explore an interactive family tree and get a picture of luxx’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. luxx’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. luxx’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
New Guinea Singing Dog
New Guinea Singing Dog
The New Guinea Singing Dog is the rarest breed in the world. These dogs have very ancient origins and share a strong resemblance to the Australian dingo.

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of luxx’s family.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. luxx’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through luxx’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A222

A2

luxx’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A222

luxx’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in New Guinea Singing Dogs.

Some other Embark dogs with this haplotype:

Dingos commonly possess this haplogroup.

Family tree

>
Explore an interactive family tree and get a picture of luxx’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. luxx’s DNA includes a story of where her father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

There are no deep ancestral lineage results for luxx on her father’s side.

Unlike recent ancestry ("What breeds are in my dog?"), the deep ancestral lineage traces the migration of a dog’s male relatives back in time to the very dawn of dogs.

Male ancestral lineage is passed down father-to-son on the Y sex chromosome. Since female dogs receive two X sex chromosomes and no Y chromosome, their male heritage line is not visible as they have no Y chromosome.

Family tree

>
Explore an interactive family tree and get a picture of luxx’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aya or ayat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GG
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CC
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of luxx’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
159
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
luxx has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that luxx has this genotype, as ALT is often used as an indicator …

Not At Risk

Good news! luxx did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that luxx does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide luxx’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! luxx is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! luxx tested clear for 8 other common genetic diseases that Embark tests for.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Von Willebrand Disease Type II
(VWF Exon 28)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Progressive Retinal Atrophy (PRA)
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Dilated Cardiomyopathy
(PDK4)
Heart

The most common acquired heart disease of dogs, this is a progressive disease of the heart ventricles: early diagnosis and treatment is key. The ventricles are the heavil…

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Other Conditions: Clear of 151

luxx is clear of 151 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of luxx’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in luxx.

Maternal Line

>
Through the DNA inherited from luxx’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far luxx’s family has traveled.

Let us know and we will contact luxx’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind luxx find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit