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Macy

Mixed Ancestry

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Genetic Breed Result

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Dachshund

The Dachshund, meaning “badger dog” in German, is a lively breed with a friendly personality and a great sense of smell. Known for their long and low bodies, they are spirited hunters that excel in both above and below-ground work. They come in three different coat varieties (smooth, wirehaired or longhaired) and can be miniature or standard size.

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Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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Miniature Schnauzer

Miniature Schnauzers are an alert and spirited breed with guard dog tendencies.

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Pug

The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.

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Dogs Like Macy

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Discover dogs who share a similar breed mix to Macy. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Chihuahua
Dachshund
Russell-type Terrier
Yorkshire Terrier
American Eskimo Dog
Miniature Schnauzer
Pug

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Here’s what Macy’s family tree may have looked like.
Macy
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Chihuahua mix Mixed Chihuahua Chihuahua / American Eskimo Dog mix Dachshund / Russell-type Terrier mix Yorkshire Terrier mix Chihuahua Chihuahua Chihuahua American Eskimo Dog mix Dachshund Russell-type Terrier Yorkshire Terrier Mixed
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Macy’s breed mix.
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Health Summary

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Macy inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Urate Kidney & Bladder Stones

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Macy inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Macy’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Macy is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Dilated Cardiomyopathy, DCM1

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Macy inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Macy will develop this disease.

Scientific Basis

Dogs with similar breeds to Macy are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Macy.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Macy inherited one copy of the variant we tested

Why is this important to your vet?

Macy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Macy has this genotype, as ALT is often used as an indicator of liver health and Macy is likely to have a lower than average resting ALT activity. As such, an increase in Macy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Thrombopathia

Identified in American Eskimo Dogs

May-Hegglin Anomaly

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Pugs

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs, Chihuahuas, and more

Progressive Retinal Atrophy, crd4/cord1

Identified in Chihuahuas and Dachshunds

Primary Lens Luxation

Identified in American Eskimo Dogs, Russell-type Terriers, and more

Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A, MPS IIIA

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 1, NCL 1

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 2, NCL 2

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 7, NCL 7

Identified in Chihuahuas

Persistent Mullerian Duct Syndrome, PMDS

Identified in Miniature Schnauzers

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Chihuahuas and Russell-type Terriers

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs, Pugs, and more

Myotonia Congenita

Identified in Miniature Schnauzers

Osteogenesis Imperfecta

Identified in Dachshunds

Intervertebral Disc Disease (Type I)

Identified in Chihuahuas, Dachshunds, and more

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Macy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1/13

Map

B1

Macy’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1/13

Macy’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in Shih Tzus, Tibetan Spaniels, Maltese, and village dogs throughout the world including Central and South America, South Asia, and the South Pacific.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Macy inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Macy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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