What is Embark?

Maggie

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See what’s hidden in the pages of Maggie’s DNA story. You can learn about the breeds that make Maggie who she is, her genetic family tree, and even go back in time to see where her ancestors came from.

Genetic Stats

Wolfiness: 0.6 % LOW Help
Predicted Adult Weight: 12 lbs Help
Genetic Age: 69 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Maggie

Breed Mix By Chromosome

Our advanced test identifies from where Maggie inherited every part of the chromosome pairs in her genome. Each chromosome section is colored to represent the breed that it comes from.

Family tree

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Explore an interactive family tree and get a picture of Maggie’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Maggie.

Maternal Line

>
Through the DNA inherited from Maggie’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Maggie’s family has traveled.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 
Large screen pedigre From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Poodle (Small) mix Mixed Poodle (Small) Poodle (Small) mix Poodle (Standard) / Bichon Frise mix Cocker Spaniel mix Poodle (Small) Poodle (Small) Poodle (Small) Mixed Poodle (Standard) mix Bichon Frise Cocker Spaniel Mixed
Explore by tapping your dog’s parents and grand parents.

Our algorithms predict this is the most likely family tree to explain Maggie’s breed mix, but this family tree may not be the only possible one.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Maggie.

Maternal Line

>
Through the DNA inherited from Maggie’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Maggie’s family has traveled.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Poodle (Small)
4 related breeds
Poodle (Small)
A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.
Related Breeds
Poodle (Standard)
Cousin breed
Maltese
Sibling breed
Havanese
Sibling breed
Bichon Frise
Cousin breed
Poodle (Standard)
5 related breeds
Poodle (Standard)
Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.
Related Breeds
Poodle (Toy)
Cousin breed
Poodle (Miniature)
Cousin breed
Maltese
Sibling breed
Havanese
Sibling breed
Bichon Frise
Cousin breed
Cocker Spaniel
4 related breeds
Cocker Spaniel
Cocker Spaniels are handsome and intelligent hunting dogs that are also well suited to life as a loving family pet.
Related Breeds
English Cocker Spaniel
Sibling breed
Sussex Spaniel
Cousin breed
English Springer Spaniel
Cousin breed
Cavalier King Charles Spaniel
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Maggie’s family.

Maternal Line

>
Through the DNA inherited from Maggie’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Maggie’s family has traveled.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Maggie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1/13

B1

Maggie’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1/13

Maggie’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in Shih Tzus, Tibetan Spaniels, Maltese, and village dogs throughout the world including Central and South America, South Asia, and the South Pacific.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Family tree

>
Explore an interactive family tree and get a picture of Maggie’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Maggie.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
KBky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aya or ayat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
BB
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
TT
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CT
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
TT
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

IGF1
II
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

IGF1R
GA
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

STC2
AA
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (E195K)
AA
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of Maggie’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Maggie.

Maternal Line

>
Through the DNA inherited from Maggie’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Maggie’s family has traveled.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
157
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Maggie has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that Maggie has this genotype, as ALT is often used as an indica…

Not At Risk

Good news! Maggie did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Maggie does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Maggie’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Maggie is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Maggie tested clear for 10 genetic conditions that are common in her breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Cocker Spaniels, Bichon Frises, but not Maggie.

Von Willebrand Disease Type II
(VWF Exon 28)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as excessive bruising or bleeding. Dogs with coagulopath…

Seen in Poodle (Small)s, Poodle (Standard)s, but not Maggie.

Progressive Retinal Atrophy (PRA)
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Poodle (Small)s, Poodle (Standard)s, Cocker Spaniels, but not Maggie.

Autosomal Recessive Hereditary Nephropathy
(COL4A4 Exon 3)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in Cocker Spaniels, but not Maggie.

Glycogen storage disease Type VII, Phosphofructokinase deficiency
(PFKM Exon 21)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in Cocker Spaniels, but not Maggie.

Gangliosidosis
GM2 Gangliosidosis (HEXB Exon 3)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Poodle (Small)s, Poodle (Standard)s, but not Maggie.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Poodle (Small)s, Poodle (Standard)s, Cocker Spaniels, Bichon Frises, but not Maggie.

Neonatal Encephalopathy with Seizures (NEWS)
(ATF2)
Brain and Spinal Cord

A neurologic disease of puppies, affected puppies are often smaller than their unaffected littermates and require intensive nursing care. Without this extra support, pupp…

Seen in Poodle (Small)s, Poodle (Standard)s, but not Maggie.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Cocker Spaniels, but not Maggie.

Osteochondrodysplasia, Skeletal Dwarfism
(SLC13A1)
Skeletal

A form of skeletal dwarfism, this causes affected dogs to have abnormally short legs but a normally sized body due to abnormal fetal skeletal maturation. As a fetus, most…

Seen in Poodle (Small)s, Poodle (Standard)s, but not Maggie.

Other Conditions: Clear of 147

Maggie is clear of 147 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Maggie’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Maggie.

Maternal Line

>
Through the DNA inherited from Maggie’s mother we can trace her ancestry back to where dogs and people first became friends. Find out how far Maggie’s family has traveled.

Let us know and we will contact Maggie’s owner and make sure she is reunited with her family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Maggie find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit