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Paxton

Mixed Ancestry

“he's a rescue. found with his litter, no info on parents”

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Genetic Breed Result

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Miniature/MAS-type Australian Shepherd

Miniature American Shepherds (also known as Miniature Australian Shepherds, or Mini Aussies) have the trainability, intelligence and energy of the larger Aussie cousins, and excel at outdoors activities and agility competitions.

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Basset Hound

Basset Hounds are widely adored, short-legged and long-bodied hunting dogs that are considered great family companions.

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Collie

Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Weimaraner

The Weimaraner is an all-purpose gun dog. The name comes from the Grand Duke of Saxe-Weimar-Eisenach, Karl August, whose court, based in the city of Weimar (now in the state of Thuringia in modern-day Germany), enjoyed hunting.

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Dogs Like Paxton

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Discover dogs who share a similar breed mix to Paxton. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Boxer
Miniature/MAS-type Australian Shepherd
Basset Hound
Collie
Golden Retriever
Weimaraner

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Changes to this dog’s profile
  • On 10/7/2017 changed name from "Paxton/Duncan (still deciding on name)" to "Paxton"
Here’s what Paxton’s family tree may have looked like.
Paxton
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Boxer mix Boxer mix Boxer Basset Hound / Golden Retriever mix Boxer Miniature/ MAS-type Australian Shepherd / Collie mix Boxer Boxer Basset Hound Golden Retriever mix Boxer Boxer Miniature/ MAS-type Australian Shepherd Collie mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Paxton’s breed mix.
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Health Summary

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Paxton inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Paxton inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Paxton’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Paxton is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Paxton inherited one copy of the variant we tested

Why is this important to your vet?

Paxton has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Paxton has this genotype, as ALT is often used as an indicator of liver health and Paxton is likely to have a lower than average resting ALT activity. As such, an increase in Paxton’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Collies and Miniature/MAS-type Australian Shepherds

Hemophilia A

Identified in Boxers

Thrombopathia

Identified in Basset Hounds

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Basset Hounds

Progressive Retinal Atrophy, prcd

Identified in Golden Retrievers and Miniature/MAS-type Australian Shepherds

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers

Collie Eye Anomaly

Identified in Collies and Miniature/MAS-type Australian Shepherds

Canine Multifocal Retinopathy, cmr1

Identified in Miniature/MAS-type Australian Shepherds

Hereditary Cataracts

Identified in Miniature/MAS-type Australian Shepherds

Urate Kidney & Bladder Stones

Identified in Miniature/MAS-type Australian Shepherds and Weimaraners

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Miniature/MAS-type Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Miniature/MAS-type Australian Shepherds

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Hypomyelination and Tremors

Identified in Weimaraners

Muscular Dystrophy

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Osteogenesis Imperfecta

Identified in Golden Retrievers

Craniomandibular Osteopathy, CMO

Identified in Miniature/MAS-type Australian Shepherds

Intervertebral Disc Disease (Type I)

Identified in Basset Hounds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Paxton’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Paxton’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Paxton’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Shar Pei dogs think A1a is the coolest!

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Through Paxton’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H10.1

Map

D

Paxton’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H10.1

Paxton’s Haplotype

Part of the D haplogroup, this widespread haplotype occurs frequently in Boxers, Chinese Shar-pei, Croatian Shepherds, and village dogs throughout the South Pacific and southeast Asia.

The D paternal lineage is common in Boxers.

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