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Renegade

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See what’s hidden in the pages of Renegade’s DNA story. You can learn about the breeds that make Renegade who he is, his genetic family tree, and even go back in time to see where his ancestors came from.

Breed mix

73.0% Siberian Husky
8.0% German Shepherd Dog
7.1% Great Pyrenees
6.6% Samoyed
2.7% Greyhound
2.6% Supermutt Help

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Genetic Stats

Wolfiness: 2.9 % HIGH Help
Predicted Adult Weight: 78 lbs Help
Genetic Age: 35 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Renegade

Breed Mix By Chromosome

Our advanced test identifies from where Renegade inherited every part of the chromosome pairs in his genome. Each chromosome section is colored to represent the breed that it comes from.

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Renegade’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 
Large screen pedigre From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky mix Siberian Husky mix Siberian Husky Siberian Husky / Samoyed mix Siberian Husky German Shepherd Dog / Great Pyrenees mix Siberian Husky Siberian Husky Siberian Husky Samoyed mix Siberian Husky Siberian Husky German Shepherd Dog mix Great Pyrenees mix
Explore by tapping your dog’s parents and grand parents.

Our algorithms predict this is the most likely family tree to explain Renegade’s breed mix, but this family tree may not be the only possible one.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Renegade’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Siberian Husky
3 related breeds
Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
Related Breeds
Alaskan Malamute
Sibling breed
Greenland Sledge Dog
Sibling breed
Samoyed
Cousin breed
Great Pyrenees
3 related breeds
Great Pyrenees
The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, and any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.
Related Breeds
Pyrenean Mastiff
Sibling breed
Pyrenean Shepherd
Cousin breed
Anatolian Shepherd Dog
Cousin breed
Samoyed
3 related breeds
Samoyed
A working breed, the Samoyed can be strong-willed at times, but above all they remain friendly, gentle, and devoted family dogs. The Samoyed was originally bred to hunt, haul sledges, and herd reindeer. Among the breed’s duties: pack hiking, tracking, and warming their owners by sleeping on top of them at night.
Related Breeds
Eurasier
Sibling breed
American Eskimo Dog
Sibling breed
Icelandic Sheepdog
Cousin breed
Greyhound
3 related breeds
Greyhound
The Greyhound is a breed unmatched in speed. This ancient dog has been used for hunting and racing, but they make wonderful companions. Surprisingly, these guys make quite the couch potato!
Related Breeds
Italian Greyhound
Sibling breed
Whippet
Cousin breed
Longhaired Whippet
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Renegade’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Renegade’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A29a

A2

Renegade’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A29a

Renegade’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in Siberian Huskies, Alaskan Malamutes, Labrador Retrievers, and village dogs from Alaska.

Some other Embark dogs with this haplotype:

Dingos commonly possess this haplogroup.

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Renegade’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Renegade’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.4

A1b

Renegade’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.4

Renegade’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs in North America and Africa. As for breeds, it occurs most frequently in Miniature Pinscher, Great Dane, and Poodle.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

  • Rogue
    Talcon
    Saarloos Wolfdog
    39% German Shepherd Dog
  • Rogue
    Talcon
    Saarloos Wolfdog
    39% German Shepherd Dog
E Locus (Mask/Grizzle/Red)
EE
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
kyky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
awaw
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
bb
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Furnishings / Improper Coat (RSPO2)
II
Chromosome 13

Confers the distinguished moustache, beard, and eyebrows characteristic of breeds like the Schnauzer, Scottish Terrier, and Wire Haired Dachshund; only one copy of the dominant F allele is required for furnishings. The FI genotype is furnished but is an improper coat carrier. A dog with two I alleles has improper coat. The mutation is a 167-bp insertion which we measure indirectly using linked markers highly correlated with the insertion.

Citations: Cadieu et al 2010

Long Haircoat (FGF5)
GG
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CC
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Natural Bobtail (T)
CC
Chromosome 1

Whereas most dogs have two C alleles and a long tail, dogs with one G allele are likely to have a bobtail, which is an unusually short or absent tail. This mutation causes natural bobtail in many breeds including the Pembroke Welsh Corgi, the Australian Shepherd, and the Brittany Spaniel. Dogs with GG genotypes have not been observed, suggesting that the GG genotype results in embryonic lethality.

Please note that this mutation does not explain every natural bobtail! While certain lineages of Boston Terrier, English Bulldog, Rottweiler, Miniature Schnauzer, Cavalier King Charles Spaniel, and Parson Russell Terrier, and Dobermans are born with a natural bobtail, these breeds do not have this mutation. This suggests that other unknown genetic mutations can also lead to a natural bobtail. If your dog does not have a CG genotype but was born with a bobtail, please email us at howdy@embarkvet.com!

Citations: Haworth et al 2001 , Hytonen et al 2009

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

0
AT RISK
0
CARRIER
159
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Renegade has two normal alleles at ALT.

Not At Risk

Good news! Renegade did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Renegade does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Renegade’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Renegade is not a carrier for any of the genetic diseases that Embark tests for.

Common conditions

Good news! Renegade tested clear for 12 genetic conditions that are common in his breed mix.
Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Siberian Huskys, German Shepherd Dogs, Great Pyreneess, Samoyeds, Greyhounds, but not Renegade.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as excessive bruising or bleeding. Dogs with coagulopath…

Seen in German Shepherd Dogs, but not Renegade.

Canine Leukocyte Adhesion Deficiency Type III
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Renegade.

Glanzmann's Thrombasthenia Type I
(ITGA2B Exon 13)
Blood

A disease of defective platelet aggregation, this causes affected dogs to bleed excessively in response to mild tissue trauma. Platelets are the first responders to tissu…

Seen in Great Pyreneess, but not Renegade.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a nonprogressive retinal disease that, in rare cases, can lead to vision loss. All known mutations lie in the BEST1 gene and are inherited in an autosomal recessi…

Seen in Great Pyreneess, but not Renegade.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in German Shepherd Dogs, but not Renegade.

X-Linked Hereditary Nephropathy
(COL4A5 Exon 35)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in Samoyeds, but not Renegade.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia

Seen in German Shepherd Dogs, but not Renegade.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)

Seen in German Shepherd Dogs, but not Renegade.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Renegade.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Siberian Huskys, German Shepherd Dogs, Great Pyreneess, Samoyeds, Greyhounds, but not Renegade.

Polyneuropathy
(NDRG1 Exon 15)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfution. Peripheral nerves relay messages between the brain and spinal cord to the rest …

Seen in Greyhounds, but not Renegade.

Other Conditions: Clear of 147

Renegade is clear of 147 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Renegade’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Renegade.

Maternal Line

>
Through the DNA inherited from Renegade’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Renegade’s family has traveled.

Let us know and we will contact Renegade’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Renegade find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit