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Rez

Mixed Ancestry

“Mostly deaf, can not hear a train on the tracks, but can hear it blow the horn.”

Current Location

Wauseon, Ohio, USA

From

Toledo, OH, USA

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Genetic Breed Result

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Staffordshire Terrier

Staffordshire Terriers, sometimes referred to as "pit bull" type, are intelligent and trainable dogs. They can have a lot of energy and are often great canine athletes!

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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American Bulldog

American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.

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Dogs Like Rez

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Discover dogs who share a similar breed mix to Rez. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Staffordshire Terrier
Siberian Husky
Labrador Retriever
Australian Cattle Dog
American Bulldog
Supermutt

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Here’s what Rez’s family tree may have looked like.
Rez
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Staffordshire Terrier mix Mixed Staffordshire Terrier American Bulldog mix Siberian Husky / Labrador Retriever mix Australian Cattle Dog mix Staffordshire Terrier Staffordshire Terrier American Bulldog Mixed Siberian Husky Labrador Retriever Australian Cattle Dog Mixed
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Rez’s breed mix.
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Health Summary

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Rez inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, prcd

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Rez inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Rez’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Rez is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

Progressive Retinal Atrophy, crd4/cord1

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Rez inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Rez’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Rez is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Rez inherited one copy of the variant we tested

Why is this important to your vet?

Rez has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Rez has this genotype, as ALT is often used as an indicator of liver health and Rez is likely to have a lower than average resting ALT activity. As such, an increase in Rez’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Cattle Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in Staffordshire Terriers

Progressive Retinal Atrophy, crd2

Identified in Staffordshire Terriers

Collie Eye Anomaly

Identified in Australian Cattle Dogs

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in American Bulldogs

Hereditary Cataracts

Identified in Staffordshire Terriers

Primary Lens Luxation

Identified in Australian Cattle Dogs

Cystinuria Type II-A

Identified in Australian Cattle Dogs

Urate Kidney & Bladder Stones

Identified in American Bulldogs, Labrador Retrievers, and more

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in Staffordshire Terriers

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bulldogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Labrador Retrievers and Siberian Huskies

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in Staffordshire Terriers

Narcolepsy

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

Myotonia Congenita

Identified in Australian Cattle Dogs

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Rez’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A211

Map

A2

Rez’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A211

Rez’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in German Shepherd Dogs, Siberian Huskies, and Alaskan Malamutes.

Dingos commonly possess this haplogroup.

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Through Rez’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7

Map

D

Rez’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7

Rez’s Haplotype

Part of the D haplogroup, this common haplotype has been found in French Bulldogs, Afghan Hounds, Bull Terriers, and village dogs spanning from South America to Africa and into the South Pacific.

The D paternal lineage is common in Boxers.

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