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Rune

Mixed Ancestry

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Genetic Breed Result

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Staffordshire Terrier

Staffordshire Terriers, sometimes referred to as "pit bull" type, are intelligent and trainable dogs. They can have a lot of energy and are often great canine athletes!

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Collie

Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.

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DNA Breed Origins

Breed colors:
German Shepherd Dog
Staffordshire Terrier
Border Collie
Golden Retriever
Rottweiler
Collie

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Here’s what Rune’s family tree may have looked like.
Rune
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS German Shepherd Dog mix Mixed German Shepherd Dog Border Collie mix German Shepherd Dog / Rottweiler mix Golden Retriever / German Shepherd Dog mix German Shepherd Dog German Shepherd Dog Border Collie Mixed German Shepherd Dog Rottweiler mix Golden Retriever German Shepherd Dog
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Rune’s breed mix.
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Health Summary

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Good news!

Rune is not at increased risk for the genetic health conditions that Embark tests.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Border Collies, Collies, and more

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in German Shepherd Dogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in German Shepherd Dogs

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Border Collies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3)

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)

Identified in Golden Retrievers

Progressive Retinal Atrophy, crd1 (PDE6B, American Staffordshire Terrier Variant)

Identified in Staffordshire Terriers

Progressive Retinal Atrophy, crd2 (IQCB1)

Identified in Staffordshire Terriers

Collie Eye Anomaly (NHEJ1)

Identified in Border Collies and Collies

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in German Shepherd Dogs

Hereditary Cataracts (HSF4 Exon 9, Boston Terrier Variant)

Identified in Staffordshire Terriers

Primary Lens Luxation (ADAMTS17)

Identified in Border Collies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in German Shepherd Dogs and Staffordshire Terriers

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A (ARSG Exon 2, American Staffordshire Terrier Variant)

Identified in Staffordshire Terriers

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Border Collies

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 Deletion, Golden Retriever Variant)

Identified in Golden Retrievers

Degenerative Myelopathy, DM (SOD1A)

Identified in Collies, German Shepherd Dogs, and more

L-2-Hydroxyglutaricaciduria, L2HGA (L2HGDH, Staffordshire Bull Terrier Variant)

Identified in Staffordshire Terriers

Muscular Dystrophy (DMD, Golden Retriever Variant)

Identified in Golden Retrievers

Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)

Identified in Border Collies

Cobalamin Malabsorption (CUBN Exon 53, Border Collie Variant)

Identified in Border Collies

Dystrophic Epidermolysis Bullosa (COL7A1, Golden Retriever Variant)

Identified in Golden Retrievers

Ichthyosis, ICH1 (PNPLA1, Golden Retriever Variant)

Identified in Golden Retrievers

Osteogenesis Imperfecta (COL1A1, Golden Retriever Variant)

Identified in Golden Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Rune’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A16/17/99/100

Map

A1a

Rune’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A16/17/99/100

Rune’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Newfoundlands, German Shepherd Dogs, and Golden Retrievers.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Rune inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Rune is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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