What is Embark?

Shiloh

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See what’s hidden in the pages of Shiloh’s DNA story. You can learn about the breeds that make Shiloh who he is, his genetic family tree, and even go back in time to see where his ancestors came from.

Genetic Stats

Wolfiness: 1.0 % MEDIUM Help
Predicted Adult Weight: 98 lbs Help
Genetic Age: 81 human years Help

Embark family

Explore other Embark dogs that have one or more breed percentages that are similar to Shiloh

Breed Mix By Chromosome

Our advanced test identifies from where Shiloh inherited every part of the chromosome pairs in his genome. Each chromosome section is colored to represent the breed that it comes from.

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Shiloh’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
Explore by tapping your dog’s parents and grand parents.

Our algorithms predict this is the most likely family tree to explain Shiloh’s breed mix, but this family tree may not be the only possible one.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Shiloh’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
DNA shows us the unique path to each of today’s recognized breeds by exposing the relatedness between them.
Labrador Retriever
4 related breeds
Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
Related Breeds
Flat-Coated Retriever
Sibling breed
Golden Retriever
Sibling breed
Chesapeake Bay Retriever
Cousin breed
Newfoundland
Cousin breed
Chow Chow
3 related breeds
Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. He can be aloof — if you’re looking for a cuddle buddy, this probably isn’t the best breed for you — and downright suspicious of strangers. But for the right person, he’s a fiercely loyal companion.
Related Breeds
Shiba Inu
Cousin breed
Chinese Shar-Pei
Cousin breed
Akita
Cousin breed

Some images and text courtesy of the AKC, used with permission.

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Shiloh’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Shiloh’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A225

A1e

Shiloh’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A225

Shiloh’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in South America and Papua New Guinea. Among breeds, we see this haplotype most frequently in Border Collies, Australian Cattle Dogs, and Australian Shepherd Dogs.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Paternal Line

>
The Y-Chromosome is only passed down from father to son. Shiloh’s DNA includes a story of where his father’s ancestors came from. We’ll show you more about how we categorize his ancestors all based of the science of genetics.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Through Shiloh’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.15

A1a

Shiloh’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.15

Shiloh’s Haplotype

Part of the large A1a haplogroup, this haplotype is found in village dogs from across the globe (outside of Asia). As for breeds, it is primarily seen in German Shepherds, Labrador Retrievers, Nova Scotia Duck Tolling Retriever. It is by far the most common haplotype in German Shepherds.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit
 

Traits report  BETA

Coat Color

A number of genetic loci are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Some other Embark dogs with this Coat Color genotype:

E Locus (Mask/Grizzle/Red)
EE or Ee or ee
Chromosome 5

Controls the characteristic melanistic mask seen in the German Shepherd and Pug as well as the grizzled "widow's peak" of the Afghan and Borzoi. Melanistic mask (Em) is dominant to grizzle (Eg) which is dominant to black (E) and red (e). Dogs that are EE or Ee are able to produce normal black pigment, but its distribution will be dependent on the genotypes at the K and A Loci. Dogs that are ee will be a shade of red or cream regardless of their genotype at K and A. The shade of red, which can range from a deep copper like the Irish Setter to the near-white of some Golden Retrievers, is dependent on other genetic factors including the Intensity (I) Locus, which has yet to be genetically mapped.

Want to help us map I Locus? If you haven't already, complete your ee pup's Embark profile with a photo! Remember, a picture is worth a thousand words!

Citations: Schmutz et al 2003 , Dreger and Schmutz 2010 ,

More information: http://www.doggenetics.co.uk/masks.html

K Locus (Dominant Black)
KBky
Chromosome 16

Causes a dominant black coat. Dogs with a dominant KB allele have black coats regardless of their genotype at the A locus; the coat color of dogs homozygous for the recessive ky allele are controlled by A locus. Alleles: KB > ky

Citations: Candille et al 2007

More information: http://www.doggenetics.co.uk/black.htm

A Locus (Agouti)
aa or ata or atat
Chromosome 24

Determines whether hair pigment is produced in a banded red and black pattern or solid black. Fawn or sable (ay) is dominant to wolf sable (aw) which is dominant to black-and-tan (at), which is in turn dominant to recessive black (a).

Citations: Berryere et al 2005 , Dreger and Schmutz 2011 ,

More information: http://www.doggenetics.co.uk/tan.html

D Locus (Dilute)
DD
Chromosome 25

Lightens a black coat to blue and a red coat to buff. A dilute phenotype requires two copies of the recessive d allele.

Citations: Drogemuller et al 2007

More information: http://www.doggenetics.co.uk/dilutes.html

B Locus (Brown/Chocolate/Liver)
Bb
Chromosome 11

Lightens a black coat to brown, chocolate or liver. The brown phenotype requires two copies of the recessive b allele. Red or cream dogs that carry two b alleles remain red or cream but have brown noses and footpads.

Citations: Schmutz et al 2002

More information: http://www.doggenetics.co.uk/liver.html

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genetic loci explain the coat phenotypes of 90% of AKC registered dog breeds.

For more information on the genetics of coat types you can refer to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Some other Embark dogs with this Coat Traits genotype:

Long Haircoat (FGF5)
GT
Chromosome 32

Confers a long, silky haircoat as observed in the Yorkshire Terrier and the Long Haired Whippet. The "T" allele is associated with longer hair.

Citations: Housley & Venta 2006 , Cadieu et al 2010

Shedding (MC5R)
CT
Chromosome 1

Affects shedding propensity in non-wire-haired dogs. Dogs with the ancestral C allele, like many Labradors and German Shepherd Dogs, are heavy or seasonal shedders, while those with one or more T allele, including many Boxers, Shih Tzus and Chihuahuas, tend to be low shedders. Dogs with furnished/wire-haired coats tend to be low shedders regardless of their MC5R genotype.

Citations: Hayward et al 2016

Curly Coat (KRT71)
CC
Chromosome 27

Causes the curly coat characteristic of Poodles and Bichons Frises. Dogs need at least one copy of the "T" allele to have a curly coat.

Citations: Cadieu et al 2010

Other Body Features

Brachycephaly (BMP3)
CC
Chromosome 32

Affects skull size and shape. Many brachycephalic or "smushed face” breeds such as the English Bulldog, Pug, and Pekingese have two copies of the derived A allele. Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele. At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the skull shape of some breeds, including the dolichocephalic Scottish Terrier or the brachycephalic Japanese Chin, appear to be caused by other genes.

Citations: Schoenbeck et al 2012

Hind Dewclaws (LMBR1)
CC
Chromosome 16

Common in certain breeds, hind dewclaws are extra, nonfunctional digits located midway between your dog's paw and hock. Dogs with at least one copy of the T allele have about a 50% of chance of having hind dewclaws.

Citations: Park et al 2008

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Some other Embark dogs with this Body Size genotype:

Body Size - IGF1
NN
Chromosome 15

The "I" allele is associated with smaller size.

Citations: Sutter et al 2007

Body Size - IGF1R
GG
Chromosome 3

The "A" allele is associated with smaller size.

Citations: Hoopes et al 2012

Body Size - STC2
TT
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (E195K)
GG
Chromosome 4

The "A" allele is associated with smaller size.

Citations: Rimbault et al 2013

Body Size - GHR (P177L)
CC
Chromosome 4

The "T" allele is associated with smaller size.

Citations: Rimbault et al 2013

Performance

Altitude Adaptation (EPAS1)
GG
Chromosome 10

Confers hypoxia tolerance. Dogs with at least one A allele are more tolerant of high altitude environments. This mutation was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.

Citations: Gou et al 2014

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit

Summary

1
AT RISK
2
CARRIER
156
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Shiloh has two normal alleles at ALT.

At Risk for 1 genetic condition

Shiloh has tested positive for 1 of the genetic diseases that Embark tests for.
What does At Risk mean?

Testing positive is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

Please consult with your veterinarian to determine the best course of action.

Condition List

Multidrug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Carrier for 2 genetic conditions

Shiloh is a carrier for 2 of the genetic diseases that Embark tests for.
What does Carrier mean?

Shiloh has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Shiloh ever has children.

Condition List

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Common conditions

Good news! Shiloh tested clear for 17 genetic conditions that are common in his breed mix.
Condition List

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as excessive bruising or bleeding. Dogs with coagulopath…

Seen in German Shepherd Dogs, but not Shiloh.

Canine Leukocyte Adhesion Deficiency Type III
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Shiloh.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A largely benign disease of red blood cell shape, elliptocytosis rarely causes symptoms. Upon examinatino of a blood smear, however, affected dogs have elongated, oval or…

Seen in Labrador Retrievers, Chow Chows, but not Shiloh.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Shiloh.

Progressive Retinal Atrophy (PRA)
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Progressive Retinal Atrophy (PRA)
Golden Retriever PRA 2 (TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Progressive Retinal Atrophy (PRA)
Cone-rod dystrophy, crd4/cord1 (RPGRIP1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in German Shepherd Dogs, Labrador Retrievers, but not Shiloh.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia

Seen in German Shepherd Dogs, but not Shiloh.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)

Seen in German Shepherd Dogs, but not Shiloh.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Shiloh.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Shiloh.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as one month, the …

Seen in Labrador Retrievers, but not Shiloh.

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Shiloh.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Shiloh.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia 1
(COL9A3)
Skeletal

A developmental disease described in the Labrador Retriever, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfism, lameness, and…

Seen in Labrador Retrievers, but not Shiloh.

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Shiloh.

Other Conditions: Clear of 139

Shiloh is clear of 139 other genetic diseases that Embark tests for.

Family tree

>
Explore an interactive family tree and get a picture of Shiloh’s family.

Breed Families

>
Dog breeds have been created over time for work and companionship. Find out about the dog breeds related to the breeds found in Shiloh.

Maternal Line

>
Through the DNA inherited from Shiloh’s mother we can trace his ancestry back to where dogs and people first became friends. Find out how far Shiloh’s family has traveled.

Let us know and we will contact Shiloh’s owner and make sure he is reunited with his family soon! Thank you for helping out our furry friends.

What’s your dog’s story?

Now that you have explored what’s behind Shiloh find out what your dog’s DNA has to tell you. Embark tells you more about your dog than you ever thought possible. Are you ready? Let’s go!

Learn more Order kit