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Xander

Mixed Ancestry

“He’s a rescue from Texas that we recently adopted we don’t know much about him or his background.”

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@x_marks_the_dog

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Catahoula Leopard Dog

The Catahoula Leopard Dog is an American working breed with origins in Louisiana. These guys come in a patchwork of colors and patterns, giving them their trademark look. They are primarily a working dog, but can make good companions with intensive socialization from an early age.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Dogs Like Xander

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Discover dogs who share a similar breed mix to Xander. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Russell-type Terrier
Australian Shepherd
Chow Chow
Catahoula Leopard Dog
Labrador Retriever
Golden Retriever
Rottweiler
Supermutt

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Changes to this dog’s profile
  • On 12/4/2017 changed handle from "xander3" to "x_marks_the_dog"
Here’s what Xander’s family tree may have looked like.
Xander
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Russell-type Terrier mix Australian Shepherd / Rottweiler mix Chow Chow mix Russell-type Terrier Catahoula Leopard Dog / Labrador Retriever mix Australian Shepherd Rottweiler mix Chow Chow Mixed Russell-type Terrier Russell-type Terrier Catahoula Leopard Dog Labrador Retriever mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Xander’s breed mix.
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Health Summary

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Xander inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, prcd

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Xander inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Xander’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Xander is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

Progressive Retinal Atrophy, crd4/cord1

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Xander inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Xander’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Xander is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Xander inherited both copies of the variant we tested

Why is this important to your vet?

Xander has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Xander's ALT activity above their current, healthy, ALT activity. As an increase above Xander’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Shepherds

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers and Labrador Retrievers

Collie Eye Anomaly

Identified in Australian Shepherds

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds

Primary Lens Luxation

Identified in Russell-type Terriers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in Australian Shepherds, Catahoula Leopard Dogs, and more

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Alexander Disease

Identified in Labrador Retrievers

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Russell-type Terriers

Degenerative Myelopathy, DM

Identified in Australian Shepherds, Golden Retrievers, and more

Narcolepsy

Identified in Labrador Retrievers

Muscular Dystrophy

Identified in Golden Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Osteogenesis Imperfecta

Identified in Golden Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds

Intervertebral Disc Disease (Type I)

Identified in Russell-type Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Xander’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B45

Map

B1

Xander’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B45

Xander’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, Doberman Pinschers, Cocker Spaniels, and village dogs in Costa Rica.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Xander’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2a

Haplotype

Hc.5

Map

A2a

Xander’s Haplogroup

A2a is a truly ancient lineage. Unlike the recent upstart A1 lineages which found their way from a few popular European males a couple hundred years ago into many dogs in many breeds, A2a shows ancient roots without major recent expansion. It is likely one of the oldest eastern Eurasian male lineages of dogs, where it has existed for thousands of years. Nowadays, it's commonly found in Tibetan Terriers and Chow Chows as well as in Southeastern Asian village dogs. The Chow Chow seems to have been depicted in sculpture over 2,000 years ago, so this is an ancient lineage indeed, and dogs with it have a long and noble pedigree! Males from this lineage have continued to be bred in similar forms and breeds for millennia.

Hc.5

Xander’s Haplotype

Part of the A2a haplogroup, this haplotype occurs most commonly in Chow Chows and village dogs from Papua New Guinea.

The large-sized Tibetan Mastiff descends from this ancient lineage.

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