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Zeke

Mixed Ancestry

“Zeke is a well traveled dog who was born in Virginia, lived in Washington DC, moved to Paris when he was 2 and now lives in London, UK. His current obsessions are baguettes and tennis balls.”

Place of Birth

Martinsville, VA, USA

Current Location

London, England, United Kingdom

From

Arlington, VA, USA

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Genetic Breed Result

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Pug

The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.

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Coonhound

Coonhounds are amazing hunting dogs that were a great help to early American settlers. With proper training they can make good companions and family dogs. It is hard to say no to those huge floppy ears!

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English Springer Spaniel

English Springer Spaniels are an energetic and loyal companion dog, bred for hunting but also popular among families.

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American Bulldog

American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.

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Dogs Like Zeke

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Discover dogs who share a similar breed mix to Zeke. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Beagle
German Shepherd Dog
Labrador Retriever
Pug
Coonhound
English Springer Spaniel
American Bulldog

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Here’s what Zeke’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Zeke’s breed mix.
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Health Summary

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Zeke has one variant that you should let your vet know about.

ALT Activity

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Zeke inherited both copies of the variant we tested

Why is this important to your vet?

Zeke has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Zeke's ALT activity above their current, healthy, ALT activity. As an increase above Zeke’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

May-Hegglin Anomaly

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, prcd

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles, English Springer Spaniels, and more

Day Blindness

Identified in German Shepherd Dogs

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in American Bulldogs

Primary Open Angle Glaucoma

Identified in Beagles

Urate Kidney & Bladder Stones

Identified in American Bulldogs, German Shepherd Dogs, and more

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Canine Fucosidosis

Identified in English Springer Spaniels

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in English Springer Spaniels

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bulldogs

Alexander Disease

Identified in Labrador Retrievers

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in English Springer Spaniels, German Shepherd Dogs, and more

Shaking Puppy Syndrome

Identified in English Springer Spaniels

Narcolepsy

Identified in Labrador Retrievers

Long QT Syndrome

Identified in English Springer Spaniels

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Intervertebral Disc Disease (Type I)

Identified in Beagles and English Springer Spaniels

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Zeke’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18

Map

A1b

Zeke’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18

Zeke’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in Central and South America, as well as French Polynesia. Among the breeds we have detected it in, this haplotype occurs most frequently in Chesapeake Bay Retrievers, Lhasa Apsos, and Pugs.

A1b is the most common haplogroup found in German Shepherds.

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Through Zeke’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8

Map

A1a

Zeke’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8

Zeke’s Haplotype

Part of the large A1a haplogroup, this very common haplotype occurs in village dogs throughout the world (including southeast Asia, which is uncommon for A1a’s). Among the 25 breeds we see this haplotype in, it occurs most frequently in Labrador Retriever, Vizsla, and English Springer Spaniel.

Dogs with A1a lineage travelled during European Colonial times.

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