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Neuromuscular

This is a Neuromuscular condition.

Congenital Myasthenic Syndrome

What is Congenital Myasthenic Syndrome?

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it has been characterized in many breeds; the genetic basis for the syndrome has only been identified in the Labrador Retriever and the Old Danish Pointer. Affected puppies from both breeds can usually play or run for up to a half hour, after which their strides get progressively shorter and the dog collapses. After resting, dogs show no ill effects. CMS is a lifelong condition that thankfully does not progress; affected dogs enjoy a good quality of life besides their exercise intolerance.

What are the signs & symptoms that develop in affected dogs?

Affected puppies can usually play or run for up to a half hour, after which their strides get progressively shorter and the dog collapses. After resting, dogs show no ill effects.

When do signs and symptoms develop?

Signs first appear in puppies, typically between 3-4 months of age.

How do vets diagnose this condition?

Genetic testing, blood work, neurological tests, and clinical signs can be used to diagnose this condition.

How is this condition treated?

CMS is a lifelong condition that thankfully does not progress; affected dogs typically enjoy a good quality of life besides their exercise intolerance.