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Integument

This is a Skin & Connective Tissues condition.

Lethal Acrodermatitis

What is Lethal Acrodermatitis?

A disease causing severe skin lesions, immune deficiency, and failure to thrive first characterized in Bull Terriers and Miniature Bull Terriers. Affected dogs can be recognized as early as 3-4 weeks of age. Due to the many complications of this condition, including skin infections, pneumonia, diarrhea, and poor growth, most affected dogs succumb to this disease early in life.

What are the signs & symptoms that develop in affected dogs?

Signs include red and ulcerated patches on the head and paws and coat color dilution. The skin lesions progress to the legs and muzzle. Respiratory signs, diarrhea, and poor growth are also common.

When do signs and symptoms develop?

Signs are often first recognized in puppies as young as 3-4 weeks of age.

How do vets diagnose this condition?

Genetic testing and clinical signs can be used to diagnose this condition.

How is this condition treated?

Unfortunately, there is no treatment for this condition. Certain medications can help control the infections for a period of time, but most puppies are euthanized early in life.