What are the signs & symptoms that develop in affected dogs?
The severity of TNS can vary, but infections can affect any of the body systems: musculoskeletal, respiratory, skin, gastrointestinal, and so forth. Fevers are common. They also have characteristic facial abnormalities including a narrow, elongated skull (described as "ferret-like") and are often smaller than unaffected littermates.
When do signs and symptoms develop?
Some puppies are brought to the vet within weeks for recurrent infections and failure to thrive, others are only diagnosed after reactions to the first set of vaccinations (6-8 weeks), and others go undiagnosed for years after treatment for mild recurrent infections.
How do vets diagnose this condition?
Genetic and laboratory testing along with clinical signs are used to diagnose this disease.
How is this condition treated?
Treatment is symptomatic and based on the body system that has the infection. There is no cure for the underlying cause of this disease.