DJ inherited both copies of the variant we tested for Hypocatalasia, Acatalasemia
DJ is not known to be at increased risk for Hypocatalasia, Acatalasemia
We do not know whether this increases the risk that DJ will develop this disease.
Research studies for this variant have been based on dogs of other breeds. Not enough dogs with the breeds in DJ have been studied to know whether or not this variant will increase DJ’s risk of developing this disease.
Catalase is important in fighting reactive oxygen species, which can cause cellular damage. Fortunately, many enzymes can break down reactive oxygen species; as such acatalasemia is usually a benign disease: however, some acatalasemic dogs suffer from what is known as Takahara’s disease, where patients have progressive mouth ulcers.
This condition is most often diagnosed in adulthood.
This condition is diagnosed through genetic testing. Oral disease can be diagnosed during a complete physical examination by your veterinarian. Some dogs require sedation for an oral exam due to pain.
No treatment is required unless mouth ulcerations are present. Ulcerations cause an increased susceptibility to oral infections, which must be monitored closely. Treatment options include regular dental care, judicious use of antibiotics, and soothing mouth sprays and rinses.
- Please follow your veterinarian's advice to maintain your dog's dental health.