Jeddak

Genetic Vet Report by embark

embarkvet.com

Test Date: January 8th, 2017

Customer-supplied information

Owner Name:
Dog Name: Jeddak
Sex: Male (intact)
Date of birth: n/a
Breed type: n/a
Breed: n/a
Breed registration: n/a

Genetic summary

Breed mix:
Gray Wolf: 91.4%
Mixed: 8.6%
Predicted adult weight: 70 lbs
Calculated from 17 size genes.

Genetic age: n/a (Date of birth unknown)
Human equivalent age based on size and other factors.

Karyogram (Chromosome painting)

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Clinical Traits

These clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.

Alanine Aminotransferase Activity result: Low Normal

Jeddak has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Jeddak has this genotype, as ALT is often used as an indicator of liver health and Jeddak is likely to have a lower than average resting ALT activity. As such, an increase in Jeddak’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.

Health Report

How to interpret these results:

AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if the dog ever has offspring.

Conditions:

Not AT RISK for any conditions tested.
Carrier
System: Other Systems
Condition: Autosomal Recessive Amelogenesis Imperfecta (ENAM)
A disease of the tooth enamel production, affected dogs have characteristic small, pointy teeth that discolor rapidly. Amelogenesis is the formation and deposition of enamel, a hard, impenetrable substance which protects teeth from acid and traumatic degradation. In the young dog, specialized cells called ameloblasts gather over the developing tooth and deposit enamel. Ameloblasts are left behind in the tooth socket as soon as a tooth erupts, which is why enamel does not renew with time. In ARAI, a defect in enamel production leads uneven enamel laydown, leading to yellowing of the underlying tooth. Teeth are also unusually small and pointy with large gaps between them. Dogs may be prone to more dental disease with this condition and should be brought to the vet for regular dental checkups.

All other health conditions tested

Jeddak tested CLEAR for all these conditions:

Information about Embark

Embark Veterinary is a canine consumer genetics company offering research-grade genetic tests to owners and breeders. Embark is a research partner of the Cornell University College of Veterinary Medicine and collaborates with scientists and registries to accelerate genetic research in canine health. The Embark test is the only comprehensive test on the market, providing results for over 160 genetic health conditions and accurate breed identification based on over 200,000 genetic markers. We strive to make it easy for customers and vets to understand, share and use their dog’s unique genetic profile to improve their pet’s health and happiness.

You can learn more on our website embarkvet.com

For enquiries please contact us at vetsupport@embarkvet.com