Canine Fucosidosis

Common signs of fucosidosis include progressive central nervous system malfunction, difficulty eating, subsequent weight loss, partial or total vision loss, behavior changes, abnormal gait, and seizures.

Onset of signs is typically between 1 and 4 years of age.

Genetic and laboratory testing are used to diagnose this condition. MRI or CT scans may be recommended to rule out other neurologic diseases.

There is no treatment for fucosidosis, and it is a fatal disease.

Talk to your vet about your dog’s canine fucosidosis result so you can work together to plan ongoing care and monitoring.

Schedule regular checkups to monitor for any changes in coordination, mobility, or behavior.

Work with your vet to provide supportive care that keeps your dog comfortable and helps them stay active and engaged.

Help your dog feel secure by keeping furniture in familiar places, using non-slip mats, and maintaining predictable daily routines.

This mutation was first described in the English Springer Spaniel.

Penetrance: This mutation is inherited in an autosomal recessive manner; that is, a dog requires two copies of the mutation to show signs of the disease.

Gene

FUCA1

Inheritance type

recessive

Clinical category

Multisystem

Citations

1. Occhiodoro and Anson 1996

• English Springer Spaniel