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We test for 270+ genetic health risks. Learn how these conditions might affect dog health.
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This condition leads to the formation of a specific type of kidney and bladder stone. These stones can irritate the urinary tract and may increase the risk of urinary discomfort or blockage.
Achromatopsia
This condition affects cone cells in the retina, which are responsible for color and daylight vision. Affected dogs may have difficulty seeing in bright light.
Achromatopsia
This condition affects cone cells in the retina, which are responsible for color and daylight vision. Affected dogs may have difficulty seeing in bright light.
Alanine Aminotransferase Activity
ALT is a liver enzyme that vets measure to monitor liver health. With this result, your dog may naturally have a lower ALT baseline. Knowing this helps your veterinarian interpret future bloodwork results more accurately.
Alaskan Husky Encephalopathy, Subacute Necrotizing Encephalomyelopathy
This neurologic condition affects how vitamin B1 is transported in the body. Because thiamine is essential for brain energy and nerve signaling, affected dogs can develop progressive neurologic signs.
Alaskan Malamute Polyneuropathy, AMPN
This progressive neurologic condition affects peripheral nerves, which carry signals between the brain and the rest of the body. As these nerves are disrupted, dogs may develop weakness, coordination problems, and changes in movement or sensation.
Alexander Disease
This neurologic condition affects astrocytes, supportive cells that help protect and nourish nerve cells in the brain. When these cells don’t function properly, normal brain support and signaling are disrupted, leading to neurologic problems.
Autosomal Dominant Progressive Retinal Atrophy
This eye condition causes degeneration of the retina. Affected dogs typically lose night vision first, followed by progressive vision loss over time.
Autosomal Recessive Amelogenesis Imperfecta, Familial Enamel Hypoplasia
This condition affects how tooth enamel forms. Teeth may appear yellow, smaller, or more pointed than usual, with wider gaps between them due to uneven or reduced enamel coverage.
Autosomal Recessive Amelogenesis Imperfecta, Familial Enamel Hypoplasia
This condition affects how tooth enamel forms. Teeth may appear yellow, smaller, or more pointed than usual, with wider gaps between them due to uneven or reduced enamel coverage.
Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy, ARHN
This progressive kidney condition affects the kidney’s filtering system, allowing protein to leak into the urine. Over time, this can lead to muscle loss, fluid buildup, and declining kidney function.
Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy, ARHN
This disorder causes the kidneys to leak protein into urine, instead of keeping it in the bloodstream. Over time, this can lead to muscle loss, fluid retention, and a decline in kidney function.
Bald Thigh Syndrome
This cosmetic condition causes hair loss on the thighs, commonly in Greyhounds. It results from changes in the hair follicles and does not typically affect a dog’s overall health.
Benign Familial Juvenile Epilepsy, Remitting Focal Epilepsy
This form of epilepsy causes seizures in young dogs, often starting early in life. The seizures are usually temporary and tend to resolve on their own as the dog matures.
Bernard-Soulier Syndrome, BSS
This condition affects platelet function, making dogs more prone to bleeding. As their platelets don’t interact normally with clotting proteins, bleeding may be more noticeable after injury, surgery, or trauma.
Canine Elliptocytosis
This is a benign condition that affects the shape of red blood cells. Instead of being round, the cells are more oval or elongated, and most dogs with this finding do not develop health problems.
Canine Fucosidosis
This condition affects how cells break down certain sugars, leading to the accumulation of waste within cells. Over time, this can lead to progressive neurologic signs as brain and nerve cells are affected.
Canine Leukocyte Adhesion Deficiency Type I, CLAD I
This is a rare condition that affects white blood cell function, making it harder for the body to fight infections. As these cells don’t respond normally, affected dogs are more vulnerable to serious illness.
Canine Leukocyte Adhesion Deficiency Type III, CLAD III
This is a rare condition that affects white blood cells and platelets, making it harder to fight infections and control bleeding. As these cells don’t respond normally, affected dogs are more vulnerable to serious illness and bleeding.
Canine Multifocal Retinopathy, cmr1
This condition causes spots on the retina but is not progressive, meaning it usually doesn’t worsen. Most dogs keep their vision, though larger areas can affect sight. New spots typically stop forming by adulthood, and some may even improve over time.
Canine Multifocal Retinopathy, cmr2
This condition causes spots on the retina but is not progressive, meaning it usually doesn’t worsen. Most dogs keep their vision, though larger areas can affect sight. New spots typically stop forming by adulthood, and some may even improve over time.
Canine Multifocal Retinopathy, cmr3
This condition causes spots on the retina but is not progressive, meaning it usually doesn’t worsen. Most dogs keep their vision, though larger areas can affect sight. New spots typically stop forming by adulthood, and some may even improve over time.
Cardiomyopathy and Juvenile Mortality
This condition affects the heart early in life, causing it to become enlarged and weakened. In some cases, it can lead to sudden death in puppies, often within the first few weeks of age.
Centronuclear Myopathy, CNM
This muscle disorder affects strength and endurance. Affected dogs may tire easily, lose weight, and develop muscle wasting over time as muscle fibers are damaged and gradually replaced with scar tissue.
Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration, NCCD
This disorder impacts the cerebellum, which helps fine-tune movement, balance, and coordination. When it doesn’t function properly, dogs may appear unsteady, uncoordinated, or have trouble with precise movements.
Cerebellar Ataxia, Progressive Early-Onset Cerebellar Ataxia
This disorder impacts the cerebellum, which helps fine-tune movement, balance, and coordination. When it doesn’t function properly, dogs may appear unsteady, uncoordinated, or have trouble with precise movements.
Cerebellar Hypoplasia
This disorder impacts the cerebellum, which helps fine-tune movement, balance, and coordination. When it doesn’t function properly, dogs may appear unsteady, uncoordinated, or have trouble with precise movements.
Chondrodysplasia
This describes a body type with shorter limbs and a proportionally longer body. It is common in some breeds, and dogs with this build typically remain healthy and active.
Chondrodystrophy and Intervertebral Disc Disease, CDDY/IVDD, Type I IVDD
This condition is associated with differences in body proportions, such as a longer back and shorter legs, and may increase the risk of spinal disc problems. Disc disease can vary in severity, from mild discomfort to more serious movement changes.
Cleft Lip and/or Cleft Palate
This developmental condition occurs when parts of the lip or roof of the mouth don’t fully fuse before birth. Depending on the area affected, dogs may have a cleft lip, a cleft palate, or both.
Cleft Palate, CP1
This developmental condition occurs when parts of the lip or roof of the mouth don’t fully fuse before birth. Depending on the area affected, dogs may have a cleft lip, a cleft palate, or both.
Collie Eye Anomaly, Choroidal Hypoplasia, CEA
This eye condition affects normal eye development. Severity varies, and while some dogs have mild changes, others may have vision impairment.
Complement 3 Deficiency, C3 Deficiency
This condition affects the immune system’s ability to fight infections. Dogs may be more susceptible to recurrent bacterial infections due to impaired immune defense.
Congenital Cornification Disorder
This rare skin condition causes painful, thickened patches of hairless, darkened skin that often appear in lines. When lesions occur on the legs, they can be uncomfortable and may lead to limping.
Congenital Dyserythropoietic Anemia and Polymyopathy
This condition affects red blood cell production and muscle function. Affected dogs may have small red blood cells, weakness in the hind legs due to muscle loss, and episodes of regurgitation.
Congenital Dyshormonogenic Hypothyroidism with Goiter
This condition affects thyroid development or hormone production from birth. When thyroid hormones are low, dogs may have slowed growth and low energy, and some may develop an enlarged thyroid gland called a goiter.
Congenital Hypothyroidism
This condition affects thyroid hormone production from birth. Affected dogs may show slowed growth, low energy, and developmental delays, but many improve with early diagnosis and treatment.
Congenital Hypothyroidism
This condition affects thyroid hormone production from birth. Affected dogs may show slowed growth, low energy, and developmental delays, but many improve with early diagnosis and treatment.
Congenital Hypothyroidism with Goiter
This condition affects thyroid hormone production and causes thyroid gland enlargement. That enlargement is called a goiter and may show up in your dog as a swelling in the neck, along with lower energy and growth delays.
Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis, Dry Eye Curly Coat Syndrome, CKCSID
This condition affects the development of the eyes, skin, hair, and nails. Affected dogs may have dry eyes, corneal ulcers, itchy skin, and thick or cracked paw pads.
Congenital Macrothrombocytopenia
This is a benign condition that affects platelet production, leading to platelets that are fewer in number and larger in size than usual. Most dogs with this finding do not develop related health problems.
Congenital Muscular Dystrophy
This condition affects a protein that helps keep muscle fibers stable. When the protein is reduced or absent, muscles are more easily damaged, leading to progressive muscle weakness and wasting over time.
Congenital Myasthenic Syndrome, CMS
This condition affects how nerves communicate with muscles. Affected dogs may have episodes of weakness or fatigue with exercise, but the condition should not worsen over time.
Congenital Myasthenic Syndrome, CMS
This condition affects how nerves communicate with muscles. Affected dogs may have episodes of weakness or fatigue with exercise, but the condition should not worsen over time.
Congenital Myasthenic Syndrome, CMS
This condition affects how nerves communicate with muscles. Affected dogs may have episodes of weakness or fatigue with exercise, but the condition should not worsen over time.
Congenital Myasthenic Syndrome, CMS
This condition affects how nerves communicate with muscles. Affected dogs may have episodes of weakness or fatigue with exercise, but the condition should not worsen over time.
Congenital Stationary Night Blindness
This condition affects how well dogs see in dim light, often causing night blindness. In some cases, vision loss can worsen over time. It is caused by changes in the retina and the tissue that helps support and protect it.
Congenital Stationary Night Blindness
This condition affects how well dogs see in dim light, often causing night blindness. In some cases, vision loss can worsen over time. It is caused by changes in the retina and the tissue that helps support and protect it.
Copper Toxicosis (Accumulating)
This condition affects the liver’s ability to remove excess copper. Over time, copper can build up in the liver and damage liver cells. Both genetic and environmental factors play a role in how the condition develops.
Copper Toxicosis (Attenuating)
This genetic variant may help lessen the effects of copper buildup in dogs that also carry the copper toxicosis risk variant ATP7B. On its own, it is not known to cause health problems.
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