Autosomal Recessive Amelogenesis Imperfecta, Familial Enamel Hypoplasia

You may notice your affected dog has small, pointy, discolored teeth with large gaps between them.

Signs can first be recognized in young dogs, but may become more noticeable as the dog ages.

Genetic testing and clinical signs are used to diagnose this disease.

There is no treatment except for regular monitoring by your veterinarian and routine dental care.

Talk to your vet about your dog’s familial enamel hypoplasia result so you can work together to plan ongoing dental care.

Brush your dog’s teeth regularly with a dog-safe toothbrush and toothpaste to help protect weakened enamel and prevent buildup.

Use dental chews, wipes, or water additives if recommended by your vet to support oral health between brushings.

Schedule regular dental checkups to monitor for signs of wear, discoloration, or sensitivity.

This mutation was first described in the Italian Greyhound.

Penetrance: This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.

Gene

ENAM

Inheritance type

recessive

Clinical category

Other Systems

Citations

1. Gandolfi et al 2013

• Italian Greyhound