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- Canine Leukocyte Adhesion Deficiency Type III, CLAD III
Canine Leukocyte Adhesion Deficiency Type III, CLAD III
FERMT3, German Shepherd Variant
- Blood
This is a rare condition that affects white blood cells and platelets, making it harder to fight infections and control bleeding. As these cells don’t respond normally, affected dogs are more vulnerable to serious illness and bleeding.
This disease is typically diagnosed in puppies or young adults when they experience chronic infections and/or bleeding following a spay or neuter.
Talk to your vet about your dog’s CLAD result, as it may influence how they monitor your dog’s health and prepare for any surgeries or procedures.
Practice good hygiene, including regular bathing with a gentle or antiseptic shampoo and routine dental care, to help reduce infection risk.
Be cautious with activities that could cause injury, like rough play at dog parks or off-leash hikes, and seek prompt veterinary care for any wounds, illnesses, or signs of infection.
This variant was first identified in German Shepherds.
Penetrance: CLAD III is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
- Gene
- FERMT3
- Inheritance type
- recessive
- Clinical category
- Hematologic
Citations
Berger Blanc Suisse
Czechoslovakian Vlcak
German Shepherd Dog
King Shepherd
Saarloos Wolfdog
Shiloh Shepherd
White Shepherd
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