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Early Bilateral Deafness
LOXHD1 Exon 38, Rottweiler Variant
- Other Systems
This genetic variant is associated with early-onset hearing loss affecting both ears. It impacts inner ear cells that are important for normal hearing, so affected dogs typically lose hearing early in life rather than as they age.
Deafness is often noted beginning at four to five months of age. However, owners may observe hearing impairment beginning at a few weeks of age. It is uncertain if this form of hearing loss is early-onset or congenital.
Talk to your vet about your dog’s deafness result so you can discuss any changes in hearing and plan care as needed.
Train your dog using visual cues or hand signals instead of verbal commands.
Avoid startling your dog by approaching gently and using vibration or light to get their attention.
Make sure your dog’s collar or leash has tags noting that they are deaf to help others interact safely and respectfully.
This variant was first identified in Rottweilers.
Penetrance: This variant has an autosomal recessive inheritance, meaning that dogs must have two copies of the variant in order to show clinical signs of Early Bilateral Deafness from it.
- Gene
- LOXHD1 Exon 38
- Inheritance type
- recessive
- Clinical category
- Other Systems
Citations
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Rottweiler