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Long QT Syndrome
KCNQ1
- Heart
The QT interval reflects how the heart’s ventricles — or main pumping chambers — contract, recover, and prepare for the next beat. This condition prolongs this interval, which means the ventricles may fall out of rhythm with the rest of the heart.
First signs of this disease are often in adulthood.
Talk to your vet about your dog’s Long QT syndrome result so you can plan regular monitoring and care.
Schedule routine cardiac screenings, such as ECGs or echocardiograms, to track heart rhythm and function over time.
Avoid overly strenuous exercise or excitement, as these can sometimes trigger fainting episodes.
With ongoing monitoring and a calm, consistent routine, many dogs with Long QT syndrome can live comfortably.
In the English Springer Spaniel, LQTS has been mapped to a mutation in the KCNQ1 gene.
Penetrance: All affected dogs were heterozygous (had only one copy) of the mutation.
- Gene
- KCNQ1
- Inheritance type
- dominant
- Clinical category
- Cardiac
Citations
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English Springer Spaniel