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Narcolepsy
HCRTR2 Intron 4, Doberman Pinscher Variant
- Brain and Spinal Cord
This condition affects sleep and wake cycles. Dogs may appear sleepier during the day and may experience brief episodes of muscle weakness with excitement, but they remain conscious and typically recover quickly.
Signs are first apparent between 1-6 months of age.
Talk to your vet about your dog’s narcolepsy result so you can plan appropriate monitoring and care.
Episodes often occur during excitement, play, or eating. Try to limit overstimulation and give your dog calm breaks throughout the day.
If your dog has an episode, make sure they are in a safe place where they won’t fall or get injured, and allow them to recover quietly.
Most dogs with narcolepsy live normal lives with a predictable routine and a calm, low-stress environment.
This mutation was first described in Doberman Pinschers.
Penetrance: This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
- Gene
- HCRTR2
- Inheritance type
- recessive
- Clinical category
- Neurologic
Citations
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Doberman Pinscher