Neonatal Interstitial Lung Disease

This disease causes fatal respiratory distress in the first days to weeks of life.

Signs develop within the first few weeks of life.

Genetic testing can diagnose this condition.

There is no treatment for this disorder.

Talk to your vet about your dog’s neonatal interstitial lung disease result so they are aware of this finding.

This condition causes severe breathing problems shortly after birth, and affected puppies rarely survive despite intensive care.

This mutation was first described in Airedales.

Penetrance: This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.

Gene

LAMP3

Inheritance type

recessive

Clinical category

Other Systems

Citations

1. Dillard et al 2020

• Airedale Terrier