Proportionate Dwarfism
GH1 Exon 5, Chihuahua Variant
- Hormones
This genetic variant may contribute to smaller adult size by affecting growth hormone activity. Other features, such as retained baby teeth, puppy-like coats, or low blood sugar, have been occasionally reported but can vary widely and may not be related.
Dogs with this variant may never show clinical signs. Smaller stature may be noticeable if the puppy grows at a different rate than littermates without this variant. Low blood sugar is a potential issue common to most toy breeds but could persist beyond four months of age. Retained puppy teeth and puppy-like coats can only be noted at more than six months of age.
Talk to your vet about your dog’s proportionate dwarfism result so you can discuss any monitoring that may be helpful as your dog grows.
Most dogs with this result live normal, healthy lives, but puppies may occasionally experience low blood sugar, especially if they miss a meal or overexert themselves.
Watch for signs of hypoglycemia such as unusual tiredness, weakness, or wobbliness. If this happens, offer a small meal or a bit of a sugar source like corn syrup or honey rubbed gently on the gums.
If your dog does not improve within a few minutes or shows severe signs such as collapse, contact your vet right away.
This variant was first described in the Chihuahua.
Penetrance: This variant is inherited in an autosomal recessive manner, meaning that a dog requires two copies of the variant to show signs of proportionate dwarfism.
- Gene
- GH1 Exon 5
- Inheritance type
- recessive
- Clinical category
- Endocrine
Citations
Featured products
Our bestselling, most comprehensive DNA test. Includes all Breed ID features, health testing, and more.
Determine the best pairings with exclusive breeder tools.
Screen for 270+ health conditions and allergy risk in 4 categories.