Recurrent Inflammatory Pulmonary Disease, RIPD

Affected dogs may present with recurrent respiratory infections, shallow breathing, coughing, nasal discharge, and fever. Affected dogs may respond well to therapy with antibiotics and other medications, but they tend to relapse quickly.

The clinical signs may start as early as at a few days of age.

Diagnosis is made based on clinical history, examination which may include radiographs (x-rays), genetic testing, and ruling out other causes of similar symptoms.

While there is no cure for RIPD, the secondary respiratory infections can most often be treated by the proper antibiotic(s). It is very important to bring affected dogs to the veterinarian promptly if the dogs exhibit signs of a respiratory infection so they can be treated quickly.

Talk to your vet about your dog’s RIPD result so you can plan appropriate monitoring and care.

Monitor your dog for signs of respiratory problems such as coughing, nasal discharge, noisy breathing, or increased effort when breathing.

Avoid exposure to smoke, dust, and other irritants that can worsen inflammation or trigger coughing.

Seek veterinary care immediately if your dog has trouble breathing, tires easily, or develops blue or pale gums.

RIPD should be differentiated from other inherited forms of recurrent pneumonia or inflammatory airway disease such as primary ciliary dyskinesia (PCD).

Penetrance: Recurrent Inflammatory Pulmonary Disease (RIPD) is recessive, meaning a dog requires two copies of the variant to show signs of the disease from the variant. This variant was first described in Rough Collies.

Gene

AKNA

Inheritance type

recessive

Clinical category

Other Systems

Citations

1. Hug et al 2019

• Collie