Dilated Cardiomyopathy, DCM

In the early stages of DCM, symptoms may not be noticed in affected dogs. DCM typically presents at the end stages of the disease, when the heart is failing and CHF develops. CHF may present with fluid in the abdomen or lungs, resulting in increased respiratory rate and effort, coughing, exercise intolerance, decreased appetite, fainting, and pale or blue gums. A murmur may be heard in some cases of DCM. Additionally, a veterinarian may observe an arrhythmia, which can increase the risk of sudden death.

In general, DCM progresses through two distinct stages: an asymptomatic stage and an overt stage, in which clinical signs attributable to congestive heart failure (CHF) become apparent. Affected dogs are typically between one to five years of age at the time of diagnosis.

A vet may use an echocardiogram (ultrasound of the heart) or radiographs (x-rays) to observe progressive dilation and/or weakness of the left or both ventricles. CHF may be diagnosed by observing an increased opacity in the lungs or abdomen on radiographs due to the presence of fluid.

Medical treatment is aimed at reducing the abnormal fluid accumulation, improving the function of the heart, and addressing arrhythmias, if present.

Talk to your vet about your dog’s dilated cardiomyopathy result so you can plan ongoing monitoring and care.

Annual echocardiograms and Holter monitoring can help detect early heart changes before symptoms appear.

Watch for signs such as fatigue, coughing, or difficulty breathing, and contact your vet if you notice any of these.

If diagnosed with DCM, avoid strenuous exercise or sudden bursts of activity, and maintain a calm, consistent routine to help reduce strain on your dog’s heart.

Keep in mind that DCM can occur due to other causes. Please consult with your veterinarian if you have any concerns, even if your dog tested clear for this variant.

Penetrance: This form of Dilated Cardiomyopathy is recessive, that is, a dog requires two copies of the variant to show signs of the disease from the variant. This early-onset form of DCM has been identified in Standard Schnauzers and Giant Schnauzers.

Gene

RBM20

Inheritance type

recessive

Clinical category

Cardiac

Citations

1. Leach et al 2014
2. Gilliam 2016

• Giant Schnauzer
• Standard Schnauzer