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Canine Multifocal Retinopathy, cmr1
BEST1 Exon 2
- Eyes
This condition causes spots on the retina but is not progressive, meaning it usually doesn’t worsen. Most dogs keep their vision, though larger areas can affect sight. New spots typically stop forming by adulthood, and some may even improve over time.
cmr1 typically develops in puppies at 11 to 16 weeks and becomes stable by the time they are 1 year old.
Talk to your vet about your dog’s CMR result so you can work together to plan their ongoing care and monitoring.
Schedule regular eye exams with your vet or a veterinary ophthalmologist to monitor for changes in your dog’s vision.
If you notice any changes in your dog’s eyesight or comfort, such as bumping into objects or hesitating in bright light, contact your vet for guidance.
This mutation was first identified in the Mastiff group.
Penetrance: CMR is inherited in an autosomal recessive manner. Dogs must have two copies of the mutation to show clinical signs.
- Gene
- BEST1/VMD2 Exon 2
- Inheritance type
- recessive
- Clinical category
- Ophthalmologic
Citations
- Guziewicz et al 2007
- Hoffman et al 2012
- http://omia.org/OMIA001554/9615/
American Bully
Australian Shepherd
Australian Shepherd
Boerboel
Alapaha Blue Blood Bulldog
American Bulldog
Bulldog
French Bulldog
Bullmastiff
Cane Corso
Dogue de Bordeaux
Great Pyrenees
Mastiff
Miniature/MAS-type Australian Shepherd
Olde English Bulldogge
Perro de Presa Canario
Terrier Brasileiro
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