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Multisystem

This is a Multisystem condition.

Canine Fucosidosis

What is Fucosidosis?

A lysosome is a structure within the cell that digests and removes waste. When the lysosome cannot recycle waste properly, the waste accumulates and causes the cell to die. Fucosidosis is specifically a buildup of fucose-containing sugar and sugar derivatives. This form of lysosomal storage disease causes progressive neurologic signs.

What are the signs & symptoms that develop in affected dogs?

Common signs of fucosidosis include progressive central nervous system malfunction, difficulty eating, subsequent weight loss, partial or total vision loss, behavior changes, abnormal gait, and seizures.

When do signs and symptoms develop?

Onset of signs is typically between 1 and 4 years of age.

How do vets diagnose this condition?

Genetic and laboratory testing are used to diagnose this condition. MRI or CT scans may be recommended to rule out other neurologic diseases.

How is this condition treated?

There is no treatment for fucosidosis, and it is a fatal disease.

What actions should I take if my dog is affected?

  • Focus on palliative therapies to increase your dog's comfort and quality of life.