What are the signs & symptoms that develop in affected dogs?
CKCSICD puppies are born with an unusually rough, curly hair coat and do not produce tears, which leads to the early symptoms of corneal ulcers, infection, and ocular discharge. As pups grow, you may also notice that their paw pads are especially thick and crusty (hyperkeratotic) and that their nails appear malformed. Over time, the paw pads can crack and slough, causing pain and lameness. The adult hair coat grows in rough, sparse, and frizzy, and the "ichthyotic" skin scaling causes thickened, darkened skin, especially around the belly area. In adulthood, it has been noted that CKCSICD dogs have a higher incidence of dental disease.
When do signs and symptoms develop?
Affected dogs are often first noted at birth, although signs continue to develop into adulthood.
How do vets diagnose this condition?
Genetic and laboratory testing are used to diagnosis this disorder.
How is this condition treated?
The symptoms of CKCSICD can be managed with artificial tears and antibiotics as needed for infected corneal ulcers, soothing baths for itchy skin, and conditioning creams for thick paw pads. Regular dental check ups are recommended for all adult dogs.