Dystrophic Epidermolysis Bullosa

skin & connective tissue

This condition arises from a mutation in Collagen Type VII. Collagens of all types anchor the layers of our skin together: they are what gives skin its springy, youthful texture (and thus are a big component of anti-wrinkle creams). Collagen Type VII has the specific job of connecting the epidermis, the surface layer of the skin, to the underlying tissues, leading to dogs with especially stretchy skin that is easily detached from the underlying tissues.

  • Signs and symptoms

    Affected dogs have skin that is injured easily and stretches more than normal.

    Signs first appear in puppies.

    Uncover health risks with Embark

    Embark Breed + Health Test

    Original price:


    Sale price:



    Embark for Breeders Dog DNA Test

    $129 - $159


  • Diagnosis

    Genetic testing, skin biopsy, and clinical signs can be used to diagnose this condition.

  • Treatment

    A variety of therapies, including skin grafts, stem cell therapy, and gene therapy, are under investigation for the treatment and prevention of EB, but these are young in development.

  • What to do if your dog is at risk


    • Trying to prevent injuries from occurring is ideal. Seek treatment immediately if your affected dog is wounded.

  • Genetic Information

    This mutation was first described in Central Asian Shepherd Dogs.

    This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.

    Gene names:

    COL7A1 ‐ chr

    Inheritance type:


  • Breeds affected

    This health condition affects the following breeds

Learn about your dog’s unique genetic health

Dog owners

Breed identification, health and trait insights, personalized care recommendations, and the world’s first canine relative finder—all in one leading dog DNA test.

Learn about the report for dog owners
Shop the test
Breeding programs

Embark’s test for breeding programs is one comprehensive DNA test designed with your needs in mind.

Learn about the report for breeders
Shop the test