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This is a Multisystem condition.

Glycogen Storage Disease Type IA, Von Gierke Disease, GSD IA

What is GSD IA?

Glycogen is the form in which our bodies store sugar: they are long, complex molecules that are primarily stored in the liver, heart, kidney, and muscle and are those tissues’ primary source of energy. In GSDs, glycogen accumulates to abnormal levels leading to enlargement and malfunction of these vital organs. Dogs with Type I GSD have very severe symptoms and are markedly hypoglycemic.

What are the signs & symptoms that develop in affected dogs?

Puppies with this disease often present severely hypoglycemic: lethargic, weak, and possibly seizing.

When do signs and symptoms develop?

Signs typically develop after only a few weeks, and most puppies with this disease die before two months of age.

How do vets diagnose this condition?

Genetic and laboratory testing used to diagnose this disease.

How is this condition treated?

There is no treatment except supportive care for the clinical signs the affected dog develops.

What actions should I take if my dog is affected?

  • Focus on palliative therapies to increase your dog's comfort and quality of life.
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