This is a Brain and Spinal Cord condition.


What is Leukodystrophy?

Leukodystrophy refers to progressive disorders of the cells that provide support, protection, and insulation to the nerve cells (neurons). This results in lesions in the brain. Destruction of initially normal tissues is a characteristic feature of leukodystrophies.

What are the signs & symptoms that develop in affected dogs?

Clinical signs occurring shortly after birth or starting at an age of under four weeks include excessive whining and crying, an exaggerated abnormal gait, difficulty swallowing, head tilt, circling, seizures, and downward pointing of the eyes.

When do signs and symptoms develop?

Affected puppies are initially normal and develop progressive neurological signs shortly after birth or starting at an age of under four weeks.

How do vets diagnose this condition?

The clinical course of the disease, genetic testing, and magnetic resonance imaging (MRI) may be used in conjunction to diagnose Leukodystrophy.

How is this condition treated?

There is no cure for Leukodystrophy; all currently available treatments are symptomatic or supportive in nature.

What actions should I take if my dog is affected?

  • Please give your dog any medication as prescribed by your veterinarian.
  • Keeping your affected dog comfortable at home is the best therapy you can provide.
  • Slings can be used to assist with their mobility, and caution should be taken to avoid falling hazards.
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