Malignant Hyperthermia
This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in body temperature (hyperthermia).
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Signs and symptoms
Affected dogs under anesthesia will have an extreme spike in body temperature and uncontrollable muscle contractions.
Signs only appear when a dog is placed under certain anesthetics.Uncover health risks with Embark
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Diagnosis
Genetic testing and clinical signs can be used to diagnose this condition.
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Treatment
This can be life threatening. Emergency treatment includes removal of the inhalant anesthetic and rapid cooling of the body with ice and fans.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s malignant hyperthermia result so it’s noted in their medical record before any anesthesia or surgery.
- Make sure all veterinarians caring for your dog are aware of this result, as certain anesthetic drugs can trigger this reaction.
- Outside of anesthesia, dogs with this result can live completely normal, active lives.
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Genetic Information
This mutation was first described in a mixed breed dog living in a university breeding colony.
This mutation is inherited in an autosomal dominant manner, meaning that one or two copies of this gene will cause the disorder.
Gene names:
RYR1 ‐ chr
Inheritance type:
dominant
Citations:
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Breeds affected
This health condition affects the following breeds
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