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This is a Skeletal condition.

Osteogenesis Imperfecta

What is OI?

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or number of their platelets, but their reduced number of platelets on a routine blood panel can be concerning. As such, dogs with inherited macrothrombocytopenia are often unncessarily subjected to a number of diagnostic tests and medications to rule out an underlying cause of their macrothrombocytopenia, including diseases of infectious, inflammatory, autoimmune, or toxic origins.

What are the signs & symptoms that develop in affected dogs?

Affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain.

When do signs and symptoms develop?

Signs are first recognized in puppies.

How do vets diagnose this condition?

Genetic testing, clinical signs, radiographs, and laboratory tests are all used to diagnose this condition.

How is this condition treated?

Currently, there is no treatment for this condition. Medications may be prescribed to help with pain.

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