This is a Brain and Spinal Cord condition.

Canine Multiple System Degeneration

What is CMSD?

A progressive neurologic disease, SERAC1 is necessary for mitochondrial function. Mitochondria are cellular structures that supply the cell with energy (ATP) and have also been linked to cerebellar disease in humans.

What are the signs & symptoms that develop in affected dogs?

Affected dogs can begin showing gait abnormalities and head tremors. This progresses to difficulty walking towards the end stages of the disease. However, they show no behavioral abnormalities and appear to be aware of their surroundings and companions.

When do signs and symptoms develop?

Signs are first apparent around 3 months of age.

How do vets diagnose this condition?

Unless a genetic basis is suspected due to the age, breed, or history of the dog, diagnostics must be performed to rule out infectious, inflammatory, or neoplastic causes.

How is this condition treated?

There is no treatment for this disorder. Certain medications may be prescribed to control symptoms.

What actions should I take if my dog is affected?

  • Keeping your affected dog comfortable and giving them the best quality of life you can are the only actions you can take at home.
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