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Skeletal

This is a Skeletal condition.

Raine Syndrome

What is Raine Syndrome?

While Raine Syndrome causes a number of craniofacial abnormalities in human patients, in dogs, the most predominant sign of the condition is significant tooth wear, which leads to irritation of the dental pulp and considerable tooth pain. Worn teeth can also have cracks, display discolored enamel, or have exposed pulp; and they often need to be extracted. In humans and dogs, Raine Syndrome has been mapped to mutations in the FAM20C gene. Embark tests for a FAM20C mutation identified in the Border Collie.

What are the signs & symptoms that develop in affected dogs?

Worn teeth that may have cracks, display discolored enamel, or exposed pulp can be seen in affected dogs.

When do signs and symptoms develop?

Signs are often first recognized in adults.

How do vets diagnose this condition?

Genetic testing and clinical signs can be used to diagnose this condition.

How is this condition treated?

Routine dental treatments including tooth extraction is used to manage this disease.