This is an Immune condition.

X-linked Severe Combined Immunodeficiency, X-SCID

What is X-SCID?

SCID dogs cannot produce functional B-lymphocytes, the cells responsible for producing antibodies and long-term "memory" of infection, as well as T-lymphocytes, which can act to destroy infected cells as well as direct other immune cells to do their job. In the absence of a functional immune system, they are extremely susceptible to infections.

What are the signs & symptoms that develop in affected dogs?

Affected dogs are extremely susceptible to infections: bacterial, viral and parasitic. Affected puppies are often lethargic with poor growth.

When do signs and symptoms develop?

Most SCID dogs are identified as puppies soon after weaning or when initially vaccinated with modified live products.

How do vets diagnose this condition?

Genetic and laboratory testing along with clinical signs are used to diagnose this disease.

How is this condition treated?

Identifying the type of infection and giving appropriate medication is the only treatment currently available. Dogs with this condition often have a markedly shortened lifespan.

What actions should I take if my dog is affected?

  • Minimizing the risk of infection is the best way to keep your affected dog healthy for as long as possible.
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