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Hematologic

This is a Blood condition.

Hemophilia B

What is Hemophilia B?

Factor IX deficiency (Hemophilia B) is a type of coagulopathy, a disorder of blood clotting. Dogs with this disorder can bleed spontaneously into their chest, abdomen, or joints. They will also develop significant bruising and profuse bleeding following a trauma or surgery.

What are the signs & symptoms that develop in affected dogs?

Affected puppies may bleed abnormally when teething. You may notice extensive bruising or bleeding that does not stop following a traumatic event. If spontaneous bleeding occurs, you may notice that your dog has swollen joints, difficulty breathing, and/or a pendulous abdomen.

When do signs and symptoms develop?

This disease is typically diagnosed in puppies or young adults when they are spayed or neutered and have a problem with clotting. However, it can be diagnosed at any age.

How do vets diagnose this condition?

Genetic or laboratory tests are performed to diagnose this condition.

How is this condition treated?

Currently, treatment for Hemophilia B focuses on prevention, vigilant monitoring, and quick treatment of spontaneous bleeds. Dogs with Hemophilia B are at great risk for uncontrollable bleeding during surgical procedures: your veterinarian should be informed so that appropriate blood products are at hand in case a transfusion is required. There is no definitive cure, though scientists have made progress correcting Hemophilia B with protein replacement and gene therapy in a laboratory setting.

What actions should I take if my dog is affected?

  • Prevention is key! Minimizing the risk of trauma and informing your veterinarian so that surgeries can be carefully planned are the best ways to prevent a catastrophic outcome.
  • Be aware of the location of the nearest emergency veterinary hospital in case of an accident.