Muscular

This is a Muscular condition.

Limb-Girdle Muscular Dystrophy 2D

What is LGMD 2D?

Muscular dystrophy is a degenerative disorder characterized by progressive muscular dysfunction. This variant in the SGCA gene causes Limb-Girdle Muscular Dystrophy 2D (LGMD 2D) in young adult dogs. Clinical signs can vary in severity and include muscle weakness, exercise intolerance, and difficulty swallowing.

What are the signs & symptoms that develop in affected dogs?

Clinical signs include exercise intolerance, progressive weakness, a stiff gait, and difficulty swallowing (dysphagia). Some animals may appear clinically unaffected, and the condition is suspected based on “incidental” blood work findings.

When do signs and symptoms develop?

This condition is likely present from birth, but you may not observe signs until the dog is 7-17 months of age.

How do vets diagnose this condition?

Genetic testing, clinical signs, and muscle biopsy can be used to diagnose LGMD. Your vet may perform specific blood tests on the basis of this result.

How is this condition treated?

At this time, care is only able to help with symptoms, and recommendations vary based on the clinical severity of the disease.

What actions should I take if my dog is affected?

  • Slings can be used to assist with dogs' mobility, and caution should be taken to avoid falling hazards.
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