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The scientists and genetic experts at Embark are hard at work making scientific discoveries to advance canine genetics. We believe in transparency, and publish those works to be available for the greater scientific community and our customers. Explore the publications from our science team below.

Publications

Kawakami T, Raghavan V, Ruhe AL, Jensen MK, Milano A, Nelson TC, et al. (2022) Early onset adult deafness in the Rhodesian Ridgeback dog is associated with an in-frame deletion in the EPS8L2 gene. PLoS One, 2022 April 06

Slavney AJ, Kawakami T, Jensen MK, Nelson TC, Sams AJ, Boyko AR. Five genetic variants explain over 70% of hair coat pheomelanin intensity variation in purebred and mixed breed domestic dogs. PLoS One, 2021 May 27

Kawakami T, Jensen MK, Slavney A, Deane PE, Milano A, Raghavan V, Ford B, Chu ET, Sams AJ, Boyko AR. R-locus for roaned coat is associated with a tandem duplication in an intronic region of USH2A in dogs and also contributes to Dalmatian spotting. PLoS One., 2021 March 23

AJ Sams, Brett Ford, Adam Gardner, Adam Boyko "Examination of the efficacy of small genetic panels in genomic conservation of companion animal populations" Wiley, 2020 April 26

ET Chu, MJ Simpson, K Diehl, RL Page, AJ Sams, AR Boyko. Inbreeding depression causes reduced fecundity in Golden Retrievers. Mamm Genome, 2019 May 21

AJ Sams and AR Boyko. Fine-Scale Resolution of Runs of Homozygosity Reveal Patterns of Inbreeding and Substantial Overlap with Recessive Disease Genotypes in Domestic Dogs. G3, 2019 January 01

PE Deane-Coe, ET Chu, A Slavney, AR Boyko and AJ Sams. Direct-to-Consumer DNA Testing of 6,000 Dogs Reveals 98.6-kb Duplication Associated with Blue Eyes and Heterochromia in Siberian Huskies. PLOS Genet, 14, e1007648., 2018 October 04

JJ Hayward, MG Castelhano, KC Oliveira, E Corey, C Balkman, TL Baxter, ML Casal, SA Center, M Fang, SJ Garrison, SE Kalla, P Korniliev, MI Kotlikoff, NS Moise, LM Shannon, KW Simpson, NB Sutter, RJ Todhunter and AR Boyko. Complex Disease and Phenotype Mapping in the Domestic Dog. Nat Comm, 7, 10460., 2016 January 22

LM Shannon, RH Boyko, MG Castelhano, E Corey, JJ Hayward, C McLean, ME White, M Abi Said, BA Anita, NB Ikombe, J Calero, A Galov, M Hedimbi, B Imam, R Khalap, D Lally, A Masta, KC Oliveira, J Randall, NM Tam, C Valeriano, FJT Cornejo, L Pérez, NB Sutter, RJ Todhunter, CD Bustamante and AR Boyko. Genetic Structure in Village Asian Domestication Origin of Dogs. Proc Natl Acad Sci U S A, 113, E2556–E2557., 2015 November 03

Have questions, comments, or want to learn more about our research? We’d love to hear from you. Reach out to us research@embarkvet.com.