Acral Mutilation Syndrome
HSAN is a rare condition affecting the dog's ability to feel pain.
-
Signs and symptoms
Affected dogs display acral analgesia, a failure to feel pain in the toes, and self-mutilation behavior including intense licking, biting, and chewing of the feet.
Signs typically are first seen in puppies. -
Diagnosis
Genetic testing and clinical signs are used to diagnose this disease. Symptoms can appear similar to dogs with a food or environmental allergy.
-
Treatment
There is no treatment for this disorder. Certain medications may be prescribed to control symptoms.
-
What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s AMS result so you can plan ongoing care and monitoring.
- Watch for signs such as excessive licking, chewing, or injury to the feet or legs, and contact your vet if you notice any of these.
- Use protective coverings or an Elizabethan collar as recommended by your vet to prevent self-injury, and keep any wounds clean and monitored.
- Provide mental enrichment and supervision to reduce boredom or stress, such as using puzzle feeders, snuffle mats, or calm training games like “find it,” where your dog searches for hidden treats.
-
Genetic Information
HSAN has been diagnosed in French Spaniels, English Springer Spaniels, English Pointers, and German Shorthaired Pointers.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
GDNF-AS ‐ chr
Inheritance type:
recessive
Citations:
-
Breeds affected
This health condition affects the following breeds
Learn about your dog’s unique genetic health
Dog owners
Breed identification, health and trait insights, personalized care recommendations, and the world’s first canine relative finder—all in one leading dog DNA test.
Learn about the report for dog ownersShop the test
Breeding programs
Embark’s test for breeding programs is one comprehensive DNA test designed with your needs in mind.
Learn about the report for breedersShop the test
