Narcolepsy
A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle tone in response to strong positive emotions. All known genetic mutations for canine narcolepsy lie in the Hypocretin receptor 2 (HCRTR2) gene. Hypocretin is a neurotransmitter involved in the regulation of appetite, arousal, and wakefulness.
-
Signs and symptoms
Other than their irregular sleep cycles and tendency to collapse when excited, narcoleptic dogs are perfectly normal dogs.
Signs are first apparent between 1-6 months of age. -
Diagnosis
Genetic testing and clinical signs are used to diagnose this disease.
-
Treatment
Affected dogs enjoy a normal lifespan and quality of life with no treatment.
-
What to do if your dog is at risk
Actions
- Most owners with narcoleptic dogs try to keep their dogs from becoming regularly overstimulated.
-
Genetic Information
This mutation was first described in Labrador Retrievers.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
HCRTR2 ‐ chr
Inheritance type:
recessive
Citations:
-
Breeds affected
This health condition affects the following breeds
Learn about your dog’s unique genetic health
Dog owners
Breed identification, health and trait insights, personalized care recommendations, and the world’s first canine relative finder—all in one leading dog DNA test.
Learn about the report for dog ownersShop the test
Breeding programs
Embark’s test for breeding programs is one comprehensive DNA test designed with your needs in mind.
Learn about the report for breedersShop the test
