Recurrent Inflammatory Pulmonary Disease, RIPD
Recurrent Inflammatory Pulmonary Disease (RIPD) is thought to occur due to a dysfunction in immune cells leading to systemic inflammation, predominantly seen in the lungs.
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Signs and symptoms
Affected dogs may present with recurrent respiratory infections, shallow breathing, coughing, nasal discharge, and fever. Affected dogs may respond well to therapy with antibiotics and other medications, but they tend to relapse quickly.
The clinical signs may start as early as at a few days of age. -
Diagnosis
Diagnosis is made based on clinical history, examination which may include radiographs (x-rays), genetic testing, and ruling out other causes of similar symptoms.
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Treatment
While there is no cure for RIPD, the secondary respiratory infections can most often be treated by the proper antibiotic(s). It is very important to bring affected dogs to the veterinarian promptly if the dogs exhibit signs of a respiratory infection so they can be treated quickly.
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What to do if your dog is at risk
Actions
- Carefully monitor your dog for signs of a respiratory infection including: coughing, nasal discharge, fever, noisy breathing, and increased respiratory rate or effort.
- Seek immediate veterinary care if respiratory distress and/or cyanotic (blue) gums are observed.
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Genetic Information
RIPD should be differentiated from other inherited forms of recurrent pneumonia or inflammatory airway disease such as primary ciliary dyskinesia (PCD).
Recurrent Inflammatory Pulmonary Disease (RIPD) is recessive, meaning a dog requires two copies of the variant to show signs of the disease from the variant. This variant was first described in Rough Collies.
Gene names:
AKNA ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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